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Biosensors
Special Issues
Flexible and Stretchable Biosensors
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Flexible and Stretchable Biosensors

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Wearable Biosensors".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 619

Special Issue Editors

Prof. Dr. Mingcen Weng

E-Mail Website
Guest Editor
Institute of Biology and Chemistry, Fujian University of Technology, Fuzhou 350118, China
Interests: soft actuator; wearable sensors; soft electronics
Dr. Peidi Zhou

E-Mail Website
Guest Editor
Institute of Smart Marine and Engineering, Fujian University of Technology, Fuzhou 350118, China
Interests: self-powered sensors; soft robotics

Special Issue Information

Dear Colleagues,

We are excited to announce the launch of a Special Issue entitled "Flexible and Stretchable Biosensors" in Biosensors. Flexible and stretchable biosensors can conform to complex surfaces, withstand mechanical deformation, and integrate seamlessly with biological systems, offering transformative solutions for healthcare, environmental monitoring, and human–machine interfaces. This Special Issue seeks to gather cutting-edge progress in the design, fabrication, and applications of flexible and stretchable biosensors.

The Special Issue spans four key areas:

  1. Materials Innovation: Novel elastomeric polymers, nanocomposites, hydrogels, and hybrid materials that enable high stretchability, biocompatibility, and functional stability.
  2. Advanced Manufacturing: Breakthroughs in micro- and nanofabrication techniques (e.g., 3D printing, laser patterning, self-assembly) for scalable, cost-effective sensor production.
  3. Biomedical Applications: In vitro or in vivo monitoring of vital signs, disease biomarkers, or therapeutic responses, with a focus on wearable platforms for personalized medicine, prosthetics, or epidermal electronics.
  4. Functional Integration: The integration of energy harvesting, wireless communication, and machine learning to enhance sensor autonomy and improve data interpretation capabilities.

By addressing these themes, the Special Issue bridges gaps between fundamental research and clinical/industrial translation while emphasizing challenges such as long-term biostability and signal integrity under dynamic conditions.

We invite submissions, including original research articles and comprehensive reviews, that advance the science and engineering of next-generation biosensing technologies. Additionally, interdisciplinary submissions are particularly encouraged to foster collaborative solutions for the considerable challenges of precision health, environmental sustainability, and beyond.

Prof. Dr. Mingcen Weng
Dr. Peidi Zhou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • flexible biosensors
  • stretchable biosensors
  • wearable devices
  • healthcare monitoring
  • human-machine interaction
  • biocompatible materials
  • soft robotics
  • polymer

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Published Papers (1 paper)

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20 pages, 4898 KB  
Article
Highly Robust and Multimodal PVA/Aramid Nanofiber/MXene Organogel Sensors for Advanced Human–Machine Interfaces
by Guofan Zeng, Leiting Liao, Zehong Wu, Jinye Chen, Peidi Zhou, Yihan Qiu and Mingcen Weng
Biosensors 2026, 16(4), 229; https://doi.org/10.3390/bios16040229 - 20 Apr 2026
Viewed by 437
Abstract
Flexible and wearable electronics require soft sensing materials that balance mechanical compliance, stable signal transduction, and durability for human–machine interfaces (HMIs). To address the limitations of single-filler systems, we propose a poly(vinyl alcohol) (PVA)/aramid nanofiber (ANF)/MXene organogel (PAM) as a multifunctional soft platform. [...] Read more.
Flexible and wearable electronics require soft sensing materials that balance mechanical compliance, stable signal transduction, and durability for human–machine interfaces (HMIs). To address the limitations of single-filler systems, we propose a poly(vinyl alcohol) (PVA)/aramid nanofiber (ANF)/MXene organogel (PAM) as a multifunctional soft platform. This design integrates a PVA physically crosslinked network with ANF for mechanical reinforcement and MXene for electrical functionality. The optimized PAM composite exhibits outstanding mechanical properties, including a fracture stress of 2931 kPa, a fracture strain of 676%, and a fracture toughness of 9.04 MJ m−3. Importantly, PAM serves as a single material platform configurable into three sensing modalities. The resistive strain sensor achieves a gauge factor of 3.1 over 10–100% strain and enables the reliable recognition of human joint movements and gestures. The capacitive pressure sensor delivers a sensitivity of 0.298 kPa−1, rapid response/recovery times of 30/10 ms, and is integrated with a wireless module to control a smart car. Furthermore, the PAM-based triboelectric nanogenerator (TENG) delivers excellent electrical outputs (Voc = 123 V, Isc = 0.52 μA, Qsc = 58 nC) and functions as a self-powered smart handwriting pad, achieving a machine-learning-based recognition accuracy of 97.6%. This work demonstrates the immense potential of the PAM organogel for advanced, self-powered HMIs. Full article
(This article belongs to the Special Issue Flexible and Stretchable Biosensors)
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