Advances in Label-Free Electrochemical Biosensing: From Surface Engineering to Health Monitoring Devices

The rapid evolution of electrochemical biosensing technologies has created new opportunities for translating fundamental discoveries into practical, real-world solutions. Label-free electrochemical strategies play a pivotal role in this progress, as they simplify sensor fabrication, reduce costs, and enable streamlined, real-time measurements. In particular, advances in surface engineering have transformed the performance and reliability of biosensors, while the development of wearable and health monitoring devices highlights their growing societal impact.
This Special Issue aims to bridge fundamental innovations in surface chemistry and interface design with applied technologies for health and beyond. We welcome contributions that expand the scientific frontiers of label-free electrochemical biosensing and demonstrate their potential for scalable, cost-effective, and sustainable deployment.
We invite original research articles and reviews on, but not limited to, the following topics:
•    Advanced surface engineering and biointerface strategies for enhanced sensor performance;
•    Nanomaterial-enabled label-free sensor architectures;
•    Sustainable and eco-friendly fabrication methods;
•    Multiplexed and high-throughput biosensing platforms;
•    Wearable, implantable, and flexible label-free electrochemical devices;
•    Real-time health monitoring (in vitro, in vivo, and point-of-care);
•    Microfluidic integration with label-free platforms;
•    Machine learning and AI for data processing and optimization;
•    Wireless, IoT-enabled, and next-generation connected biosensors.

Dr. Soha Ahmadi
Guest Editor

Manuscript Submission Information

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