Application of Biosensors in Cell and Tissue Analysis

Dear Colleagues,

Cell and tissue based assay targeting drug-receptors interactions has proven to significantly increase the success rates in clinical trials. The main reason being the more in vivo like conditions that elucidates the strengths and weaknesses of a drug.

This Special Issue aims at state of the art biosensors for cells and tissues within drug development. The scope is to gathering assays that mimics in vivo conditions as much as possible, hence features such as label-free, kinetics, flow, serological, temperature etc are important. For example, the diffent pH levels in the blood stream and inside cells affect interaction properties. On and off-target interactions are crucial for PK and PD studies, and consequently for efficacy and side effects. We encourage publications combining cell or tissue based biosensor with traditional methods, hence elucidating the added value of this new biosenors for drug development.

Dr. Teodor Aastrup
Dr. Ahmed Ibrahim
Prof. Dr. Ian A. Nicholls
Guest Editors

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