DNA Damage and Repair in Cancer Treatment
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 219
Special Issue Editors
Interests: DNA damage; DNA repair; cancer; radiation therapy; bioinformatics
Special Issues, Collections and Topics in MDPI journals
Interests: radiation-induced chromosome aberrations; DNA repair; hadrontherapy; radiosensitization and radioprotection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue intends to showcase the most recent research on the importance of mitigation of DNA damage and maintenance of genome integrity in cancer therapy. Normal-tissue response is the limiting factor for curative radiotherapy. Hence, strategies to mitigate radiation-induced DNA damage in normal cells are crucial to abate unwanted sequelae. In fact, failure in maintaining DNA integrity is a key factor in radiation-induced carcinogenesis and poor radiotherapy outcome. Thus, radiotherapy strives to achieve normal-tissue protection while impairing cancer cell repair ability. Therefore, in this Special Issue, we welcome original fundamental research carried out by pre-clinical in vitro and/or in vivo approaches, as well as up-to-date reviews on these topics, with special emphasis on the novel frontiers in the fields of anticancer molecular targets.
Prof. Dr. Alexandros Georgakilas
Prof. Dr. Lorenzo Manti
Guest Editors
Manuscript Submission Information
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Keywords
- ionizing radiation
- DNA damage
- DNA repair
- genomic instability
- patient radioprotection
- tumour radiosensitization
- radiation-induced carcinogenesis
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