Oxygen Homeostasis, Oxidative Stress, and Inflammation in Kidney Health and Disease
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (20 February 2025) | Viewed by 280
Special Issue Editors
Interests: hemoglobin; cytoglobin; androglobin; oxygen; hypoxia; gene regulation; HIF; EPO
Special Issues, Collections and Topics in MDPI journals
Interests: redox imbalance; oxidative stress; neuroprotection; diabetes; mitochondrial dysfunction; protein oxidation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The kidneys are organs with high energy demands due to their heavy workload, which involves the filtration and reabsorption of nutrients, minerals, and electrolytes. The kidneys are also involved in the regulation of blood pressure and pH and vitamin D maturation and erythropoiesis. As such, the kidneys are constantly exposed to numerous insults, which can trigger acute kidney injury (AKI) and chronic kidney disease (CKD), including diabetic nephropathy. While it has been generally established that hypoxia, redox imbalance, oxidative stress, mitochondrial dysfunction, and inflammation are all implicated in the pathogenesis of AKI and CKD, the detailed mechanisms behind them still need to be unraveled in order to explore novel therapeutic targets to combat kidney disease. For this purpose, we are launching this Special Issue, and we welcome research focusing on any aspect of the above-mentioned pathological processes. Both original research articles and review articles will be considered.
We look forward to receiving your submissions.
Prof. Dr. David Hoogewijs
Dr. Liang-Jun Yan
Guest Editors
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Keywords
- acute kidney injury
- chronic kidney disease
- diabetic nephropathy/diabetic kidney disease
- inflammation
- hypoxia
- redox homeostasis
- redox imbalance
- oxidative stress
- mitochondrial dysfunction
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