Advances in Redox Biochemistry of Cognitive Impairment Pathogenesis and Treatment
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 13
Special Issue Editors
Interests: intermittent hypoxia to protect brain and heart from ischemic injury; kidney preservation for transplant
Interests: intermittent hypoxia to preserve cognitive function
Interests: redox imbalance; oxidative stress; neuroprotection; diabetes; mitochondrial dysfunction; protein oxidation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The mammalian brain is exquisitely vulnerable to oxidative stress due to its absolute dependence on oxidative metabolism to meet its immense energy requirements makes. If not detoxified by neuronal antioxidant networks, reactive oxygen intermediates generated by neuronal mitochondria, activated microglia or invasive neutrophils instigate neuronal injury culminating in cognitive impairment. This Special Issue will spotlight cutting-edge research discoveries about the complex redox biochemistry of the brain and the pro- and antioxidant mechanisms of cognitive impairment pathogenesis vs. treatment. The Special Issue aims to broaden our understanding of the processes underlying cognitive impairment and the mechanisms vs. limitations of potential treatments.
We welcome the submission of all manuscript types supported by the journal (including Articles, Reviews, Brief Research Reports, Commentaries, etc.) on the redox biochemistry of cognitive impairment and its treatment, pertaining but not limited to the following themes:
- The contributions of oxidative stress and inflammation to cognitive impairment.
- Advances in cell-based, animal and human-derived models to study cognitive impairment and its treatment.
- The impacts of systemic inflammation on brain redox state and cognitive function.
- Redox-based interventions targeting the mechanisms of cognitive impairment.
- Identification of redox-based biomarkers to detect cognitive decline and evaluate treatments.
- Translating preclinical discoveries into clinical interventions for cognitive impairment.
Prof. Dr. Robert T. Mallet
Dr. Xiangrong Shi
Dr. Liang-Jun Yan
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aging
- antioxidants
- brain
- cognitive decline
- inflammation
- models
- reactive oxygen species
- therapeutic interventions
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