Special Issue "Understanding the Potential of Host Defense Peptides in Treating Cancer"
Deadline for manuscript submissions: 31 October 2020.
Interests: cancer; immunology; host defense peptides; phytochemicals; natural products; microbiology
Interests: cancer biology; immunology; inflammation; host defense peptides; phytochemicals; iron metabolism; natural products
Cancer is the second leading cause of death globally. The need is urgent to discover novel treatments for cancer that are curative and not associated with considerable toxicity. Identification of suitable drug targets is a major obstacle in cancer treatment strategies. Host defense peptides (HDPs) are biomolecules typically containing several cationic and hydrophobic amino acids that interact with the cell membrane, resulting in anti-microbial, anti-cancer, and immune modulatory activities. Anti-cancer peptides (ACPs) exhibit increased toxicity toward cancer cells compared to normal cells. The structure of ACPs impacts their mechanism of action, so better understanding ACPs will have clinical relevance.
It is my pleasure to invite you and your teams, as experts from diverse backgrounds (medicine, pathology, immunology, molecular biology, and biochemistry), as well as those working in cancer research, to contribute original research or review articles to this Special Issue. We are especially interested in articles that cover studies on the identification, roles, and molecular mechanisms of action of ACPs, and translational approaches to the use of ACPs of clinical relevance in cancer.
Dr. Melanie R. Power Coombs
Dr. David W. Hoskin
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- host defense peptides
- anti-cancer peptides
- peptide delivery