Chemistry and Biochemistry of Glycosylation
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biomacromolecules: Carbohydrates".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 2091
Special Issue Editors
Interests: glycobiology; glycosylation
Interests: mass spectrometry; glycobiology
Interests: organic chemistry; mass spectrometry
Interests: glycobiology; cancer biology; carcinogenesis; environmental toxicology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Glycosylation plays a crucial role in the co- and post-translational modifications of more than 90% of proteins in eukaryotic cells. Glycans expressed on cell surface participate in many important cellular events by interacting with their corresponding proteins or receptors. Alterations in carbohydrate compositions are known to correlate with the changes in protein stability and clearance, as well as various important biological functions including cell-cell adhesion, inflammation, infection of bacteria and viruses, tumorigenesis, and metastasis. Transformation of malignancy is frequently accompanied by an intense alteration in the structures of oligosaccharides on proteins of cell surface. The molecular changes that occur upon malignant transformation can be characterized using specific monoclonal antibodies and mass spectrometry. The changes in glycosylation include both the under- and overexpression of naturally occurring glycans, as well as neo-expression of glycans normally restricted to embryonic tissues. Hence, this special issue aims to collect research papers or reviews that can improve our knowledge on chemistry and biochemistry of glycobiology, as well as functional glycomics. You are welcome to submit your current research work.
Dr. Chuan-Fa Chang
Dr. Hsin-Yi Wu
Dr. Pang-Hung Hsu
Dr. Yung-Kuo Lee
Guest Editors
Manuscript Submission Information
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Keywords
- glycobiology
- chemistry
- biochemistry
