Protein Acetylation and Methylation—from Gene Regulation to Epigenetics, Metabolism, and Beyond
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates".
Deadline for manuscript submissions: 17 July 2026 | Viewed by 1
Special Issue Editor
Interests: mass spectrometry; epigenetics; disease mechanisms; cancer; one-carbon metabolism; histone methylation; hypoxia; biochemical analysis; methodology development; proteomics
Special Issue Information
Dear Colleagues,
Post-translational modifications such as protein acetylation and methylation play pivotal roles in regulating chromatin dynamics, transcriptional activity, and cellular metabolism. These reversible chemical marks modulate the function of histone and non-histone proteins, integrating environmental signals with gene expression programs. Recent advances in mass spectrometry, structural biology, and chemical biology have revealed how acetylation and methylation coordinate diverse biological processes, from epigenetic inheritance and cellular differentiation to disease pathogenesis and metabolic reprogramming. This Special Issue aims to highlight emerging insights into the molecular mechanisms, regulatory networks, and physiological consequences of protein acetylation and methylation, fostering a comprehensive understanding of their roles across cellular systems and disease contexts.
In this Special Issue, original research articles and reviews are welcome.
I look forward to receiving your contributions.
Dr. Kangling Zhang
Guest Editor
Manuscript Submission Information
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Keywords
- protein acetylation
- protein methylation
- histone modification
- epigenetics
- gene regulation
- chromatin remodeling
- metabolism
- signal transduction
- post-translational modification (PTM)
- proteomics
- cancer biology
- systems biology
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