Multifunctional Nanocarriers for Advanced Therapy and Diagnosis

Dear Colleagues,

The advancement of drug-delivery systems has significantly enhanced therapeutic efficacy, minimized adverse effects, and facilitated precision medicine. This Special Issue seeks original research articles, reviews, and communications on recent progress in Multifunctional Nanocarriers for Advanced Therapy and Diagnosis that respond to internal or external stimuli, actively target disease sites, or dynamically adapt to the biological environment.

We particularly encourage contributions addressing any of the following themes:

• Design, synthesis, and physicochemical characterization of nanocarriers.
• Functionalization with targeting ligands and biomimetic coatings.
• Stimuli-responsive behaviors, including responses to pH, redox conditions, enzymes, temperature, light, magnetic fields, ultrasound, mechanical forces, and hybrid triggers.
• Strategies for overcoming biological barriers, such as achieving circulation stability, evading immune clearance, facilitating extravasation, enhancing tumor penetration, improving intracellular trafficking, and promoting lysosomal escape.
• Controlled or on-demand drug release profiles, co-delivery of multiple active agents, including small molecules, biologics, and nucleic acids, as well as theranostic nanocarriers.
• Pre-clinical evaluation, including in vitro, ex vivo, and in vivo biodistribution, pharmacokinetics, safety and efficacy assessments, and mechanistic studies.

Dr. Buddhadev Layek
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.