Cutting-Edge Perspectives on Protein and Enzyme Engineering
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 847
Special Issue Editors
2. Key Laboratory of Systems Bioengineering of the Ministry of Education, Tianjin University, Tianjin 300072, China
Interests: protein materials; industrial enzyme; cell factories; protein production
Special Issue Information
Dear Colleagues,
Protein and enzyme engineering is the process of developing useful or valuable proteins such as protein materials, industrial enzymes, and therapy proteins. It includes technologies for engineering protein, producing protein, and purifying protein. Directed evolution has emerged as a powerful strategy to engineer various protein properties. In addition, machine learning and deep learning have developed rapidly and have been applied in protein engineering such as in protein function prediction, enzymes directed evolution, and so forth. Additionally, synthetic biology provides more maneuverability for protein design and synthesis. In the process of protein engineering, unnatural amino acids may be also included, via newer methods, such as expanded genetic code, which allows for encoding novel amino acids in genetic code. For protein production and purification, the construction of efficient cell factories, development of specific chassis cells, and separation tags are current research hotspots. This Special Issue is aimed at providing an overview of the most recent advances in the field of protein and enzyme engineering.
The journal will be accepting contributions covering potential topics including, but not limited to, the following:
- protein material;
- protein expression system;
- protein separation and purification;
- enzymes directed evolution;
- therapy proteins engineering;
- protein computational design;
- machine learning used for protein engineering;
- molecular dynamics simulations of proteins;
- unnatural amino acids incorporation;
- protein post-translation modification;
- protein structures and mechanisms;
Dr. Haishan Qi
Dr. Haoran Yu
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- protein engineering
- protein material
- enzyme evolution
- therapy protein
- protein expression
- machine learning
- unnatural amino acids
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