The Role of Extracellular Vesicles (EVs) in Cell-to-Cell Communication
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 241
Special Issue Editor
Interests: cancer pathogenesis; genomics; tumor suppressor genes, DNA damage and repair; genetic and epigenetic alteration and drug resistance; anti-cancer drug screening
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) are membrane-bound particles released by cells that play a crucial role in cell-to-cell communication. In the context of cancer, EVs are involved in various stages of tumorigenesis:
- Initiation: EVs can carry oncogenic factors such as proteins, RNAs, and microRNAs that promote the transformation of normal cells into cancerous cells. They facilitate the creation of a tumor-friendly environment by modulating immune responses and altering the behavior of surrounding cells.
- Progression: During tumor progression, EVs contribute to the growth and survival of cancer cells. They support angiogenesis (the formation of new blood vessels) and help in remodeling the extracellular matrix, which provides structural support for tumor expansion.
- Metastasis: EVs play a pivotal role in metastasis by preparing distant sites for tumor cell colonization, a process known as pre-metastatic niche formation. They aid in the detachment of cancer cells from the primary tumor, their survival in the bloodstream, and their invasion into distant organs.
This Special Issue’s scope is the three stages of tumorigenesis listed above, and we are accepting original research articles, reviews, and brief reports that focus on these areas.
Dr. Yuqian Yan
Guest Editor
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Keywords
- extracellular vesicles (EVs)
- tumorigenesis
- initiation
- progression
- metastasis
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