The Unexpected Antitumor Properties of Our Pharmaceutical Agents

A special issue of Biology (ISSN 2079-7737).

Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 504

Special Issue Editors


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Guest Editor
Anesthesiology and Intensive Care Department, U1138 Metabolism, Cancer and Immunity (G. Kroemer lab), 39 rue Camille Desmoulins, 94805 Villejuif, France
Interests: metabolism; cellular and molecular biology; cell signaling; cell death modality; epigenetic; cancer; immunity; oncoimmunology; anesthesiology; intensive care
Special Issues, Collections and Topics in MDPI journals
Faculty of Medicine, University of Paris Sud, 94270 Kremlin-Bicêtre, France
Interests: cancer; immunology; cell death; apoptosis; autophagy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recently, some agents belonging to classical pharmacopeia such as analgesics, anti-inflammatory drugs, or antibiotics have shown an incredible antitumor response when used alone or in combination with conventional anticancer treatments. In addition, a surprising improvement in survival rates was observed after the injection of these agents during oncological surgery. Consequently, the benefits for patients are major. By potentiating the immune antitumor response, these agents offer the opportunity to improve patient outcomes without the side effects induced by traditional antitumor agents. Furthermore, adjuvant treatments during surgery can control residual tumor cells and decrease the risk of relapses. Finally, the possibility to employ some agents that are already marketed and whose features are well-known, enable the application of their antitumor properties immediately. Investigations into other agents that may induce the same effect and understand how these molecules interact with the immune system represent a challenging purpose. Clinicians need to be aware of the existence of such properties to give patients the maximum chance of recovery.

This Special Issue will gather original research, reviews, and commentaries dealing with preclinical and clinical discoveries in the use of classical agents as anti-cancer therapeutics, including techniques and methods that contributed to these breakthroughs.

Dr. Lucillia Bezu
Dr. Oliver Kepp
Guest Editors

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Keywords

  • cancer
  • antitumor response
  • immunology
  • pharmacopeia

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