Biomarkers for Cancer Immunity
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: 31 August 2025 | Viewed by 108
Special Issue Editor
Interests: tumor microenvironment; tumor immunity; cancer immunotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer immunotherapy, such as immune checkpoint inhibitors and CAR-T cells, has revolutionized cancer treatment, but the outcomes differ widely, with only a few patients achieving lasting benefits. This inconsistency is due to the complexity and heterogeneity of the tumor microenvironment (TME), which current therapies targeting classical pathways like CTLA-4 and PD-1/PD-L1 and limited immune cell populations struggle to address. To address this issue, there is a need to identify novel biomarkers, better understand diverse immune cell populations, and develop combinatory strategies. These efforts will help overcome resistance mechanisms and improve outcomes in cancer immunotherapy.
This Special Issue aims to inspire new insights into cancer immunity mechanisms, novel biomarkers, and effective combinational strategies for cancer immunotherapies. We welcome submissions of original research, review articles, mini-reviews, and perspectives that explore the fundamental mechanisms of cancer immunotherapy and the therapeutic potential of novel combination strategies.
Dr. Xuyao Zhang
Guest Editor
Manuscript Submission Information
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Keywords
- tumor microenvironment
- tumor immunity
- systems immunology
- resistance mechanism
- biomarkers
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