Advances in Cell and Experimental Biology: Cellular Organelle Stress and Homeostasis in Physiology and Diseases
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 558
Special Issue Editor
Interests: autophagy; integrated stress response; proteotoxic stress response; organelle homeostasis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cellular organelles are specialized compartments within cells that carry out specific functions. For instance, mitochondria are responsible for energy production, the endoplasmic reticulum synthesizes proteins, the Golgi apparatus processes and packages proteins and lipids, cilia sense the environment and move fluids, centrioles are involved in cell division and the DNA damage response, and autophagy lysosomes remove damaged proteins and organelles. Throughout evolution, cells have developed finely tuned mechanisms to adapt to organelle stress and maintain homeostasis. These mechanisms include the unfolded protein response (UPR) and the integrated stress response for the endoplasmic reticulum (ER), the mitochondrial UPR (mtUPR), and mitophagy, which is the autophagic removal of damaged or excess mitochondria. Additionally, there are responses for Golgi stress, DNA damage via centrosomes, and selective autophagy for various cellular organelles, including the endoplasmic reticulum, mitochondria, lipid droplets, Golgi complex, peroxisomes, ribosomes, centrioles, centrosomes, basal bodies, and the cell nucleus. Disruptions in these cellular stress responses and organelle homeostasis can lead to cell dysfunction, resulting in cell death or senescence, and contribute to various diseases such as metabolic disorders, cancer, and neurodegenerative diseases. In this Special Issue, we invite review and original research manuscripts that focus on organelle stress responses in cell physiology and disease. We warmly welcome presenters from the 6th International Conference on Cell and Experimental Biology, as well as all researchers interested in contributing to these exciting topics.
Prof. Dr. Wen-Xing Ding
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- autophagy
- integrated stress response
- proteotoxic stress response
- organelle homeostasis
- ubiquitination
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