Function of Steroid Receptors and Their Epigenetic Co-Regulators in Tissue Homeostasis
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".
Deadline for manuscript submissions: 31 March 2027 | Viewed by 193
Editors
Interests: metabolism; fertility; functional genomics
Interests: nuclear receptor biology; transcriptional regulation; chromatin and epigenetic regulation; prostate biology and disease; mouse models of tissue homeostasis
Special Issue Information
Dear Colleagues,
Steroid receptors play a major role in regulating numerous physiological processes, including development, metabolism, fertility, and stress responses. As ligand-dependent transcription factors, these receptors represent important pharmacological targets for the treatment of various pathologies, such as inflammatory diseases and certain cancers. Their activity is tightly controlled by epigenetic coregulators, including chromatin remodelers, histone modifiers, and DNA methylation regulators. Recent advances in functional genomics and epigenomics shed light on how these dynamic interactions shape transcriptional repertoires in different tissues, thus conferring tissue-specificity to steroid receptors. However, many questions remain regarding the molecular mechanisms that link hormonal signaling, chromatin architecture, and cellular homeostasis in physiological and pathological contexts. This Special Issue aims to bring together original research articles and reviews exploring the functions of steroid receptors and their epigenetic coregulators in tissue homeostasis. Particular attention will be paid to translational studies linking mechanistic, multi-omics, and physiological characterizations in different biological systems.
Dr. Delphine Duteil
Guest Editor
Dr. Qingshuang Cai
Co-Guest Editor
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Keywords
- steroid receptors
- epigenetic co-regulators
- chromatin remodeling
- transcriptional regulation
- tissue homeostasis
- hormone signaling
- nuclear receptors
- epigenomics
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