Endothelial Remodeling in Vascular Diseases
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 366
Special Issue Editor
Interests: endothelial inflammation; endothelial permeability; vascular remodeling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular diseases are conditions that affect heart and blood vessels. They are the leading cause of death worldwide and in the U.S. According to a recent report from the CDC, one person dies every 34 seconds in the United States from cardiovascular disease. Therefore, there is a need to search for novel mechanisms and therapeutics to reduce mortality and improve patients’ quality of life. The endothelium is a key barrier between the blood and other cells in the tissues. Endothelial dysfunction is a key variable in the pathogenesis of all cardiovascular diseases and chronic inflammatory diseases. This eventually leads to adaptive mechanisms and changes in the structure of the vessel called vascular remodeling. Reorganization of endothelial cells (endothelial remodeling) is the core of vascular remodeling that includes increased endothelial cell size, migration, proliferation, apoptosis, and changes to the surrounding extracellular matrix.
On these grounds, this Special Issue of the journal Biology has the main objective to gather papers that have both a strong basic research background and a clear translational potential. Therefore, studies exploring novel molecular mechanisms involving endothelial cell dynamics in vascular remodeling in patients with various underlying cardiovascular diseases are welcome in this Special Issue.
In summary, this Special Issue aims to underscore the key importance of endothelial remodeling in various cardiovascular diseases.
Dr. Hemant Giri
Guest Editor
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Keywords
- endothelial proliferation
- endothelial migration
- endothelial cell apoptosis
- endothelial permeability and inflammation
- endothelial cell metabolism
- endothelial injury
- endothelial dysfunction
- endothelial cell infection
- endothelial cell heterogeneity
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