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Applied System Innovation publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Applied System Innovations Using Graph-Based Artificial Intelligence Techniques

edited by

Weixi Gu

and

Weiwei Jiang

submission deadline 30 Aug 2025 | Viewed by 304 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; graph embedding; graph convolutional network; graph attention network

(This special issue belongs to the Section Artificial Intelligence)

Smart Factories and Energy Transition

edited by

Zoran Jurkovic

Marko Fabić

, Damir Purković, Sandro Doboviček and

Sasa Sladic

submission deadline 20 Sep 2025 | Viewed by 207 | Submission Open

Keywords: smart factories; collaborative robots; programable logic controllers; artificial intelligence applications; energy communities; energy transition

Advancements in Deep Learning and Its Applications

edited by Patrícia Ramos and Jose Manuel Oliveira

submission deadline 30 Sep 2025 | 19 articles | Viewed by 100872 | Submission Open

Keywords: deep learning applications; artificial intelligence; neural network architectures; transformers; generative models; real-world AI implementation

(This special issue belongs to the Section Artificial Intelligence)

Feature Papers in the ‘Applied Systems on Educational Innovations and Emerging Technologies’ Section

edited by

Chun-Yen Chang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2765 | Submission Open

Keywords: applied systems in emerging technologies; generative artificial intelligence systems for educational innovation; smart electromechanical system analysis and design for educational innovation; mathematical control theory and systems for educational innovation; computer-aided systems for educational innovation; e-learning systems for educational innovation; engineering design methodology and optimization for educational innovation; computers and human– machine interaction in educational innovation; internet technology in educational innovation; intelligent robots for educational innovation; Internet of Things (IoT) in educational innovation; machine learning in educational innovation

(This special issue belongs to the Section Applied Systems on Educational Innovations and Emerging Technologies)

Feature Papers in the ‘Industrial and Manufacturing Engineering’ Section

edited by

Cheng-Fu Yang

submission deadline 30 Oct 2025 | 3 articles | Viewed by 5599 | Submission Open

Keywords: advanced manufacturing technologies; supply chain management and logistics optimization; quality control and six sigma; sustainable manufacturing and green technologies

(This special issue belongs to the Section Industrial and Manufacturing Engineering)

AI-Driven Educational Technologies: Systems and Applications

edited by Nikos Antonopoulos and

Stamatios Papadakis

submission deadline 20 Nov 2025 | Viewed by 329 | Submission Open

Keywords: artificial intelligence; education; human– computer interaction

(This special issue belongs to the Section Applied Systems on Educational Innovations and Emerging Technologies)

Advanced Technologies and Methodologies in Education 4.0

edited by

Sarantos Psycharis

Konstantinos Kalovrektis

and

Apostolis Xenakis

submission deadline 30 Nov 2025 | 5 articles | Viewed by 14329 | Submission Open

Keywords: physical computing; educational technologies; educational robotics; learning machines; STEAM

Large Language Models: Theories, Methodologies and Real-World Applications in Healthcare

edited by

Flavio Bertini

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2086 | Submission Open

Keywords: artificial intelligence in healthcare; LLMs in healthcare; fine-tuning LLMs for screening; LLMs for medical knowledge retrieval; explanations of LLMs for healthcare applications

(This special issue belongs to the Section Medical Informatics and Healthcare Engineering)

Advanced Control Strategies and Optimization for Renewable Energy Systems

edited by

Mohsen Pourkiaei

submission deadline 10 Dec 2025 | Viewed by 85 | Submission Open

Keywords: renewable energy systems; optimization algorithms; intelligent control strategies; energy management systems; sustainable development; smart grids; energy storage optimization; hybrid energy systems; machine/deep learning in control; predictive control; distributed energy resources; power system resilience

Advancing Healthcare Through Intelligent Clinical Decision Support Systems: Techniques, Applications, and Future Directions

edited by

Alberto Comesaña-Campos

Jorge Cerqueiro Pequeño

, María Luísa Torres-Durán, Alberto Fernandez-Villar and

Manuel Casal-Guisande

submission deadline 30 Dec 2025 | 5 articles | Viewed by 14473 | Submission Open

Keywords: intelligent clinical decision support systems (ICDSS); Healthcare decision-making; artificial intelligence in healthcare; machine learning and deep learning in ICDSS; expert systems in the definition of ICDSS; expert systems in the definition of ICDSS; hybrid systems applied in ICDSS; testing and validation of ICDSS; future work lines and advances in ICDSS

(This special issue belongs to the Section Medical Informatics and Healthcare Engineering)

Evolution of Electric Motors: Current Trends and Future Prospects for Industrial Applications

edited by

Theoklitos Karakatsanis

and

Athanasios Karlis

submission deadline 30 Dec 2025 | 2 articles | Viewed by 5081 | Submission Open

Keywords: permanent magnet synchronous motors; induction motors; industrial applications; power electronics; control theory; fault-tolerant electric machines; fault diagnosis; smart sensors; predictive maintenance; condition monitoring

Recent Developments in Data Science and Knowledge Discovery

edited by

Wenbing Zhao

submission deadline 30 Dec 2025 | 4 articles | Viewed by 4848 | Submission Open

Keywords: big data analytics; data mining; knowledge discovery; natural language processing; image recognition; predictive analytics; anomaly detection; decision-making

(This special issue belongs to the Section Artificial Intelligence)

Enhancing Smart Manufacturing: Process Innovation and Safety Management in the Digital Factory Era

edited by

Mario Di Nardo

Valentina Popolo

and

Marianna Madonna

submission deadline 30 Dec 2025 | Viewed by 104 | Submission Open

Keywords: human– machine collaborative systems; challenges and limitations for smart manufacturing; data quality and quality in information management systems; defining performance measures for smart manufacturing systems; digital transformation for manufacturing supply chains; sustainability for smart manufacturing; smart manufacturing for process safety management practices; AI applications for industrial safety; Industry 5.0 for process enhancement and safety management; work systems and human factors in the era of digital transformation; optimization for smart manufacturing processes and advanced safety systems performance

(This special issue belongs to the Section Industrial and Manufacturing Engineering)

Privacy-Preserving Models and Systems in Blockchain

edited by

Christine Hennebert

submission deadline 20 Jan 2026 | Viewed by 7 | Submission Open

Keywords: privacy-enhancing technologies (PETs) through blockchain; cryptographic anonymous credentials; secure multiparty computation; advanced digital signatures; ring signatures; and blind signatures; attribute-based credentials; PETs within supply chains; medical domain; transportation; etc.; usage of blockchain and IPFS; privacy-enhancing information system architectures; data security at storage and during transfer

(This special issue belongs to the Section Information Systems)

Recent Advances in Internet of Things and Its Applications

edited by

Jahan Hassan

Sayed Amir Hoseini

and

Syed Danial Ali Shah

submission deadline 20 Feb 2026 | Viewed by 114 | Submission Open

Keywords: wireless; Internet of Things; precision agriculture; IoT sensors; soil monitoring; crop health; automated irrigation; mining; environmental sensing; vehicular technology; traffic management; remote patient monitoring; wearable health devices; real-time diagnostics; personalized healthcare; IoT security; SCADA; telemetry systems; industrial automation

Autonomous Robotics and Hybrid Intelligent Systems

edited by

Calin Ciufudean

Tamara Nestorović

and

Olena Hrybiuk

submission deadline 25 Feb 2026 | Viewed by 37 | Submission Open

Keywords: autonomous robotics; artificial intelligence in robotics; intelligent control systems; machine learning for robotics; fuzzy logic controllers; neural networks; evolutionary computation; swarm intelligence; path planning and navigation; human– robot interaction; multi-agent systems; service robotics; industrial automation; robotics in healthcare; AI for cyber– physical systems

(This special issue belongs to the Section Control and Systems Engineering)

Reviews of Critical and Emerging Technologies for Applied System Innovation

edited by

Daswin De Silva

submission deadline 20 Mar 2026 | Viewed by 53 | Submission Open

Keywords: emerging technologies; critical technologies; systematic review; scoping review; narrative review; meta analysis; artificial intelligence; quantum computing; biotechnologies; advanced/unconventional computing; advanced materials; integrated networking; nanomanufacturing; semiconductors and microelectronics; space technologies; AI robotics; humanoid robotics; augmented reality; virtual reality; neural technologies

Advances in Mathematical Models and Computational Intelligence for Transportation System Planning and Management

edited by Yan Sun and Maoxiang Lang

submission deadline 30 May 2026 | 2 articles | Viewed by 2473 | Submission Open

Keywords: transportation system planning; transportation system management; transportation system operations; optimization model; game model; intelligent algorithm; system simulation

(This special issue belongs to the Section Artificial Intelligence)

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