Special Issue "Current Concept and Emerging Treatments in Oral Diseases"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 31 December 2020.

Special Issue Editor

Dr. Gianluca Tenore
Guest Editor
Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy
Interests: oral medicine; oral surgery; oral cancer; laser

Special Issue Information

Dear Colleagues,

I would like to invite you to submit a contribution to a Special Issue of Applied Science: “Current Concept and Emerging Treatments in Oral Diseases”. In recent years, significant progress has been achieved in the diagnosis and treatment of oral diseases. The management objectives of oral diseases have become more directed toward prevention and early diagnosis. In addition, the minimally invasive approach using all available methods has become a favorable approach to raise the quality of life and to maintain the maximum respect of our patients. These concepts should be reflected not only in the local clinical aspect but also on the systemic clinical overview. The presence of many medically compromised patients who take one or more drug therapies and need a tailored treatment plan due to the high risk of significant comorbidities is observed in daily dental practice. The topic of interest of this Special Issue is all valid updates on the prevention, diagnosis, and treatment of oral diseases for both dentoperiodontal and osteomucosal structures.

The topics of interest of this Special Issue include valid updates on (but not limited to) the management of:

  1. Oral cancer patients;
  2. Oral potentially malignant disorders;
  3. Medication-related osteonecrosis of the jaws;
  4. Patients undergoing radio- and chemotherapy;
  5. Medically compromised patients;
  6. Oral infections;
  7. Patients with special needs;
  8. New technologies for oral health.

All original articles, case reports, and review articles are welcome for submission.

Dr. Gianluca Tenore
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Oral cancer
  • Risk factors
  • Diagnosis
  • Potentially malignant disorders
  • Osteonecrosis
  • Mucositis
  • Oral infections
  • Therapy
  • Surgery
  • Laser
  • Rehabilitation
  • Radiotherapy
  • Chemotherapy
  • Molecular target drug

Published Papers (1 paper)

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Open AccessFeature PaperArticle
Tobacco, Alcohol and Family History of Cancer as Risk Factors of Oral Squamous Cell Carcinoma: Case-Control Retrospective Study
Appl. Sci. 2020, 10(11), 3896; https://doi.org/10.3390/app10113896 - 04 Jun 2020
Cited by 1
The aim of the study is to observe retrospectively the correlation between Oral Squamous Cell Carcinoma (OSCC) and risk factors; including tobacco, alcohol and Family History of Cancer (FHC). A total of 478 patients were included retrospectively from the database of the Department [...] Read more.
The aim of the study is to observe retrospectively the correlation between Oral Squamous Cell Carcinoma (OSCC) and risk factors; including tobacco, alcohol and Family History of Cancer (FHC). A total of 478 patients were included retrospectively from the database of the Department of Oral Sciences and Maxillofacial Surgery, Sapienza University of Rome. A Test Group (TG) consisted of 239 patients with a confirmed diagnosis of OSCC. A Control Group (CG) consisted of 239 patients without history and/or diagnosis of oral cancer. The logistic regression models were used to calculate the adjusted Odd Ratios (ORs) associated with alcohol, tobacco and FHC; including the General Family History of Cancer (GFHC) and Family History of Head and Neck Cancer (FHHNC) and their 95% Confidence Intervals (CI). The high rate of tobacco consumption was associated with an OR of 1.035 (95% CI 1.001–1.070) and a statistical significance (p = 0.041). Drinker patients showed a significant risk of developing OSCC (p = 0.05) and the OR was 1.035 (95% CI 1.010–1.061). The GFHC was associated with a marginal risk of OSCC with an OR of 1.095 (95% CI 0.953–1.259), without significance (p = 0.199). The FHHNC showed a notable risk increase with an OR of 1.871 (95% CI 0.902–3.882), without significance (p = 0.092). Alcohol and tobacco may be associated with an increase in the risk of OSCC. Full article
(This article belongs to the Special Issue Current Concept and Emerging Treatments in Oral Diseases)
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