Dietary Bioactive Compounds and Their Neuroprotective Potential
A special issue of Applied Sciences (ISSN 2076-3417).
Deadline for manuscript submissions: 30 November 2025 | Viewed by 27
Special Issue Editors
Interests: neuroprotection; hippocampus; bioactive compounds; memory and cognitive function; natural antioxidants; obesity and diabetes models; neuropeptides
Interests: nutrition; physiology; metabolism; meat quality; milk quality; feedstuffs; herbs; feed additives; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bioactive compounds—naturally occurring, non-nutrient constituents found in a wide variety of plant- and marine-based foods—have seen increased scientific interest due to their remarkable neuroprotective potential. These compounds, including polyphenols, flavonoids, terpenoids, alkaloids, carotenoids, and omega-3 fatty acids, are capable of modulating critical cellular pathways involved in brain health. Their pleiotropic actions encompass antioxidant, anti-inflammatory, antiapoptotic, and neurogenic effects, all of which are highly relevant in the context of neurodegeneration and age-related cognitive decline.
This Special Issue aims to highlight cutting-edge research on the role of dietary bioactive compounds in protecting the nervous system. We invite contributions that explore their mechanisms of action, structure–activity relationships, bioavailability, gut–brain interactions, and potential for translation into functional foods or nutraceutical interventions. Particular interest will be given to studies targeting neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and other chronic neurological conditions, where bioactive compounds may offer promising preventive or therapeutic benefits.
Dr. Małgorzata Komar (Matysek)
Dr. Edyta Kowalczuk-Vasilev
Guest Editors
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Keywords
- bioactive compounds
- neuroprotection
- dietary bioactives
- polyphenols
- flavonoids
- brain health
- oxidative stress
- neuroinflammation
- neurodegeneration
- functional foods
- nutraceuticals
- cognitive decline
- gut–brain axis
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