Special Issue "Synthesis and Application of Microcapsules II"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemistry".

Deadline for manuscript submissions: 15 September 2021.

Special Issue Editor

Prof. Dr. Fabien Salaün
Guest Editor
ENSAIT Ecole Nationale Supérieure des Arts et Industries Textiles, Roubaix, France
Interests: materials chemistry; polymer chemistry; textile engineering; microencapsulation; technical textiles; surface functionalization; smart coating; smart textile
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Special Issue Information

Dear Colleagues,

Microencapsulated systems based on polymers or inorganic shell and active substances have emerged as good candidates for a broad range of applications.

The design of microparticles as a “smart” polymeric system has drawn increasing interest over the last few years due to their considerable potential when it comes to protecting different types of active agents in widely varied application fields, such as medicine, biomedical, pharmaceutical, textile, agricultural, food, and printing. The recent progress in controlled microencapsulation techniques has greatly facilitated the synthesis of well-defined microcapsules with a tailored functionality. Microcapsule shells and their functionality may finally be used to modulate surface functions. All these benefits are currently fully exploited for new tailored microparticles, for applications in drug delivery, self-healing, thermal energy storage, flame retardancy, cosmetics, functional coating, and material science, where they are used for the design of functional, responsive, or high-added-value materials.

This Special Issue is motivated by the observed increasing interest shown by various research groups in this field. Thus, considering your prominent contribution to this interesting research topic, I would like to cordially invite you to submit an article to this Special Issue. This Special Issue will publish full research papers, communications, and review articles. It will offer a global vision of researchers from universities, research centers, and industry worldwide working on microencapsulation and share the latest results in synthesis and characterization, as well as applications in basic and industrial processes. My goal is to collect comprehensive reviews from leading experts and up-to-date research from notable groups in the community, which will hopefully serve as a useful source of information for researchers. 

Prof. Dr. Fabien Salaün
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Microencapsulation process and characterization
  • Nanoencapsulation process and characterization
  • Coating process of encapsulated materials
  • Colloid and formulations
  • Encapsulation in layer-by-layer polyelectrolyte films
  • Sol–gel chemistry
  • Emulsion-based processes (phase coacervation, interfacial polymerization, in situ polymerization, liposomes, solvent evaporation, etc.)
  • Encapsulation in the pharmaceutical, biomedical, cosmetics, food, and textile fields, among others
  • Hydrogels, polymers, sol–gel glasses, inorganic–organic hydrid materials, porous materials, multifunctional particles, micro and nanocapsules, and other host matrices and materials supports of interest
  • Functional coating

Published Papers (1 paper)

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Open AccessArticle
Preparation of an Oxygen-Releasing Capsule for Large-Sized Tissue Regeneration
Appl. Sci. 2020, 10(23), 8399; https://doi.org/10.3390/app10238399 - 25 Nov 2020
Sufficient oxygenation for prevention of cellular damage remains a critical barrier to successful tissue engineering, especially in the construction of a large-sized tissue despite numerous attempts to resolve this issue in recent years. There have been a number of hypothetical solutions to this [...] Read more.
Sufficient oxygenation for prevention of cellular damage remains a critical barrier to successful tissue engineering, especially in the construction of a large-sized tissue despite numerous attempts to resolve this issue in recent years. There have been a number of hypothetical solutions to this problem, including the use of artificial oxygen carriers, induction of vascularization, and fabrication of oxygen-generating biomaterials. All of these efforts have improved the efficiency of oxygen supply, but none have been able to support the large tissue mass required for clinical application. Necrosis, which often occurs during hypoxic stress, is one of the most significant limitations in large-sized tissue regeneration. In this study, we developed an oxygen producing capsule using hydrogen peroxide (H2O2), PLGA (poly (lactic-co-glycolic acid) and alginate, and also evaluated the capsule as a model of a large-sized tissue. Firstly, H2O2 was microencapsulated by PLGA, and subsequently the H2O2-PLGA microspheres were embedded into a catalase-immobilized alginate capsule of 5.0 mm in diameter. The alginate capsules of a fairly large size were characterized for their oxygenation capability to cells embedded such as human umbilical vein endothelial cells (HUVECs) by HIF-1α and VEGF expression. The results of this study confirmed that in the oxygen-releasing capsule composed of H2O2 polymeric microspheres and catalase-bound alginate, HUVEC cells successfully survived in the hypoxic state. These results demonstrated that our oxygen producing system containing H2O2-PLGA microspheres could be a useful oxygenating biomaterial for engineering large-sized tissue. Full article
(This article belongs to the Special Issue Synthesis and Application of Microcapsules II)
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