Lipid-Based Nanocarriers: Present Situation and Prospects for the Future
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Nanotechnology and Applied Nanosciences".
Deadline for manuscript submissions: closed (30 November 2018) | Viewed by 11441
Special Issue Editor
Interests: drug delivery systems; nanoparticulate lipid matrix systems; nanocarriers for the transport of active molecules
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lipid-based nanocarriers (solid lipid nanoparticles, nanostructured lipid carriers, vesicular nanocarriers including liposomes, niosomes, transfersomes, and ethosomes) have recently gained enormous interest for their potential pharmaceutical applications. They may in fact provide controlled drug release and allow the targeting of drugs to specific areas. Furthermore, their lipid properties (e.g., high solubilizing potential, biocompatibility, biotolerability, biodegradability, and distinct route of absorption) may significantly improve the bioavailability of very poorly water-soluble drugs for a set of administration routes. Generally speaking, the incorporation of active compounds in lipid-based nanocarriers has helped to boost the therapeutic efficacy of drugs and to improve their pharmacokinetic parameters, as a result of their prolonged release from these systems. These features of the lipid-based nanocarriers (sustained drug release and modulation of the drug efficacy) have shed a light of hope for the treatment of chronic diseases. Therefore, the interest in lipid-based nanocarriers has been growing, as demonstrated by the number of related patents and scientific papers in the literature.
The Special Issue of the journal Applied Sciences entitled “Lipid-based nanocarriers: present situation and prospects for the future” wishes to cover the recent advances in the development of lipid-based nanocarriers aimed at the delivery of drugs by different routes of administration, underscoring the extraordinary value of this drug-carrying system in improving the bioavailability and therapeutic efficacy of the encapsulated drugs.
Prof. Dr. Carmelo Puglia
Guest Editor
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Keywords
- Colloidal drug delivery systems (CDDS);
- Nanostructured lipid carriers (NLC);
- Solid lipid nanoparticles (SLN);
- Liposomes;
- Niosomes;
- Transfersomes;
- Ethosomes;
- Drug delivery;
- Prolonged release;
- Controlled release;
- Drug targeting;
- Improved drug bioavailability;
- Main administration routes
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