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Edible and Functional Films for Food and Biomedical Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: 20 September 2026 | Viewed by 920

Special Issue Editors


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Guest Editor
Department of Basic Science, UPIITA-Instituto Politécnico Nacional, Mexico City, Mexico
Interests: emulsion and encapsulation technologies; properties and stability of spray-dried powders; functional biopolymeric films incorporating microbial agents for antimicrobial applications

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Guest Editor
Department for Sustainable Food Process (DiSTAS), Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122 Piacenza, Italy
Interests: antioxidants; bioactives; biotechnology; encapsulation; enzymes; extraction; food engineering; food waste; functional; fruit; rheology; shelf-life; valorisation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue will highlight the latest advances in edible films and coatings, covering their functionalization, characterization, and applications in both the food and biomedical fields. It will address the development of novel biopolymeric matrices and innovative processing and functionalization strategies. Materials of interest include natural polymers such as carbohydrates, lipids, and proteins, as well as composites; incorporation of active agents such as antimicrobials, antiseptics, antioxidants, vitamins, and emerging bioactives; and the design of coatings with tailored mechanical, barrier, and controlled-release properties. We welcome research on applications aimed at extending food shelf life, improving safety and sensory quality, and enhancing nutritional value, as well as interdisciplinary studies that expand edible films and coatings into biomedical uses such as wound healing, tissue regeneration, and controlled drug delivery. Sustainability, biodegradability, biocompatibility, and scalability will be highly considered for inclusion in this Special Issue. Both original research articles and comprehensive reviews are encouraged, focusing on approaches that combine innovation, functionality, and innovative solutions to existing challenges.

Dr. Yunia García Tejeda
Prof. Dr. Giorgia Spigno
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • edible films and coatings
  • biopolymeric matrices
  • active packaging
  • antimicrobial films
  • controlled release systems
  • wound healing applications
  • encapsulation technology
  • functional biomaterials
  • sustainable materials
  • toxicity, biocompatibility, and regulatory considerations

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Published Papers (1 paper)

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Research

17 pages, 3795 KB  
Article
Bdellovibrio bacteriovorus Patches Accelerate Wound Closure in Diabetic Mice Faster than Conventional Antibiotic Therapy
by Christian Mariel Sáenz-Santos, Yunia Verónica García-Tejeda, Mario Alberto Rodríguez-Pérez, Rosario Munguía-Fuentes, Carolina Estefania Chávez-Murillo and Oscar Eduardo Cigarroa-Mayorga
Appl. Sci. 2026, 16(7), 3305; https://doi.org/10.3390/app16073305 - 29 Mar 2026
Viewed by 504
Abstract
Diabetic wounds infected with multidrug-resistant bacteria represent a major clinical challenge due to delayed healing and limited therapeutic options. In this study, we evaluated the therapeutic efficacy and biosafety of a biopolymeric skin patch loaded with the predatory bacterium Bdellovibrio bacteriovorus HD100 in [...] Read more.
Diabetic wounds infected with multidrug-resistant bacteria represent a major clinical challenge due to delayed healing and limited therapeutic options. In this study, we evaluated the therapeutic efficacy and biosafety of a biopolymeric skin patch loaded with the predatory bacterium Bdellovibrio bacteriovorus HD100 in a murine model of diabetic wounds infected with Pseudomonas aeruginosa. In vitro assays demonstrated that B. bacteriovorus HD100 reduced P. aeruginosa populations by approximately 3 log units within 48 h. In vivo, diabetic mice treated with the B. bacteriovorus-loaded patch achieved complete wound closure within 12±1 days, compared with 16±1 days in mice treated with conventional antibiotic therapy (piperacillin/tazobactam, 16 mg/kg; single dose). Non-diabetic mice treated with biopolymeric patches, with or without the predatory bacterium, exhibited complete wound closure within 9–10 days. Molecular analysis by PCR revealed no detectable dissemination of B. bacteriovorus DNA to internal organs (liver, spleen, kidney, or brain), indicating the systemic biosafety of topical application. Overall, these results demonstrate that B. bacteriovorus-based skin patches significantly accelerate wound closure in infected diabetic wounds and represent a promising localized biological alternative to conventional antibiotic therapy. Full article
(This article belongs to the Special Issue Edible and Functional Films for Food and Biomedical Applications)
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