Advances of Hyaluronan in Tissue Regeneration
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".
Deadline for manuscript submissions: closed (29 November 2024) | Viewed by 3047
Special Issue Editors
Interests: hyaluronan; tissue regeneration; cell signaling; extracellular matrix; inflammation; stem cell; hydrogel; tumor microenvironment
Interests: hyaluronan; cell signaling; inflammation; growth factor; extracellular matrix; tumor microenvironment
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hyaluronan is one of the major polysaccharides in the extracellular matrix ubiquitously present in the joints and other parts of the human body, including the skin, eyes, bones, and cartilage. This polymer is essential for normal homeostasis and is implicated in multiple inflammatory and degenerative diseases and cancer. It interacts with different hyaladherins, receptors, and growth factors and modulates the major phases of tissue regeneration, including inflammation, proliferation (fibrogenesis and angiogenesis), and remodeling to restore the structure and function of the tissue. Remarkably, the hyaluronan-enriched matrices affect cellular processes. Thus, this sugar molecule has received significant attention in biomedical research, and cutting-edge discoveries in hyaluronan-based medical devices (e.g., hydrogels, injections, dermal fillers) and drug discovery (biologics, small molecules, peptides) for a wide range of therapeutic purposes promise a revolutionary change in regenerative medicine.
This Special Issue will publish high-quality original research papers and review articles on breakthrough applied research exploring the importance of hyaluronan in tissue regeneration. The emphasis should be given to the therapeutic application of hyaluronan-based medical products in different degenerative diseases and studies elucidating the role of hyaluronan and hyaluronan-binding proteins in the underlying mechanisms of cellular process of tissue regeneration. The following topics will be covered in this Special Issue:
- Hyaluronan signaling in tissue regeneration;
- Wound healing;
- Hyaluronan impact on inflammation and degenerative diseases;
- Hyaluronan mechanobiology;
- Stem cells;
- Biomedical application of hyaluronan-based medical products in tissue regeneration.
Dr. Kaustuv Basu
Prof. Dr. Paraskevi Heldin
Dr. Davide Vigetti
Guest Editors
Manuscript Submission Information
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Keywords
- hyaluronan
- tissue regeneration
- wound healing
- cell signaling
- hydrogel
- dermal filler
- stem cell
- inflammation
- degenerative disease
- regenerative medicine
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