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Advancements in Natural Compounds: Antimicrobial, Antioxidant, and Therapeutic Potentials

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: 10 October 2025 | Viewed by 45

Special Issue Editors


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Guest Editor
1. Department of Biochemistry and Pharmacogenomics, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland
2. Department of Pharmaceutical Sciences, Collegium Medicum, Jan Kochanowski University in Kielce, IX Wieków Kielc 19a, 25-516 Kielce, Poland
Interests: biochemistry; molecular biology; obesity; diabetes; cancers; pharmacy; active substances; natural products; natural therapies
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Pharmaceutical Sciences, Collegium Medicum, Jan Kochanowski University in Kielce, IX Wieków Kielc 19a, 25-516 Kielce, Poland
Interests: plant biotechnology; pharmaceutical botany; cosmetic plants; medicinal plants; phytochemistry; bioactive compounds; natural products; natural antioxidants

Special Issue Information

Dear Colleagues,

This Special Issue focuses on recent advancements in the study of natural compounds, particularly their antimicrobial, antioxidant, and therapeutic potentials. Natural compounds derived from plants, fungi, marine organisms, and microorganisms have garnered significant attention due to their bioactive properties and potential applications in medicine, pharmaceuticals, and functional food industries. This Special Issue will explore bioactive molecules, their mechanisms of action, and their role in combating microbial infections, oxidative stress, and chronic diseases.

Preparations such as extracts contain a diverse range of phytomolecules, offering multiple benefits in terms of the study of metabolic diseases such as diabetes, cardiovascular disease (CVD), and cancer. Natural compounds hold significant therapeutic potential as they can influence multiple pathways, including the PI3K signaling pathway, the inhibition of the GLUT1 transporter, and other mechanisms that reduce oxidative stress.

One major advantage of in vitro cultivation is its ability to produce valuable bioactive compounds in a controlled environment and this approach ensures a sustainable and consistent supply of phytochemicals, overcoming environmental constraints such as seasonal variations and habitat loss. Additionally, in vitro techniques enable the enhancement of specific bioactive compounds through elicitation strategies or genetic modifications, making them a reliable and efficient method for obtaining plant-derived therapeutic agents.

This Special Issue will also delve into innovative extraction and purification techniques that enhance the efficacy and bioavailability of these compounds. It will cover studies on the synergistic effects that arise between natural compounds and conventional drugs, as well as their potential applications in drug development and alternative medicine. By bringing together researchers from fields such as pharmacology, microbiology, biochemistry, and food science, this collection aims to present cutting-edge findings that could shape future therapeutic strategies and promote the sustainable use of natural resources.

Prof. Dr. Małgorzata Wrzosek
Dr. Marta Klimek-Szczykutowicz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural bioactive compounds
  • antimicrobial activity
  • antioxidant mechanisms
  • phytochemicals and secondary metabolites
  • functional foods and nutraceuticals
  • medicinal plants and ethnopharmacology
  • fungal and microbial metabolites
  • oxidative stress and chronic diseases
  • synergistic effects with conventional drugs
  • green extraction techniques
  • alternative medicine and natural therapies

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Published Papers

This special issue is now open for submission.
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