Redox Metabolism in Ecophysiology and Evolution, 2nd Edition

Dear Colleagues,

The evolution of complex endogenous antioxidant systems in aerobic organisms was driven by the gradual accumulation of oxygen in the Earth's atmosphere. This intricate system developed to effectively cope with oxygen and its reactive byproducts. Beyond a simple battle between reactive species and defensive enzymatic and non-enzymatic antioxidants, the redox metabolism and aerobic life are inseparable. Redox signaling is mediated by non-radical redox metabolites, redox-sensitive transcription factors, and redox-sensitive proteins, forming an interconnected network of signaling pathways. These pathways have been discovered to play crucial roles in various essential processes in aerobic organisms, ranging from circadian rhythms to aging and lifespan regulation. Indeed, oxidative stress significantly influences the life history of living organisms, and environmental stressors have the potential to disrupt the delicate balance of redox reactions, thereby triggering compensatory adaptive responses.

The modulation of the redox metabolism has been extensively documented in diverse species across the phylogenetic spectrum, as they face a wide array of environmental stressors, including temperature fluctuations, water scarcity, variations in oxygen levels, exposure to UV radiation, and pollution, among others. In natural settings, these environmental factors often exhibit variable time frames, such as daily and seasonal fluctuations. Therefore, comprehending how antioxidant systems adaptively respond to environmental perturbations is crucial for understanding the role of oxidative stress in the ecology and adaptability of specific taxonomic groups.

We are delighted to invite you to submit your research to this exciting Special Issue, which aims to explore the ecological and evolutionary implications of oxidative stress and its interaction with the environment. This Special Issue serves as a continuation of the successful first volume, which you can find using the following link: https://www.mdpi.com/journal/antioxidants/special_issues/redox_ecophysiology_evolution.

Dr. Marcelo Hermes-Lima
Dr. Daniel Carneiro Moreira
Dr. Marko Prokic
Guest Editors

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• oxidative stress ecology
• reactive oxygen and nitrogen species
• hormesis
• redox biology
• environmental stress