Special Issue "Selenium and Animal Health"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (31 March 2019).
Interests: Nutritional physiology, selenium, selenoproteins, antioxidants, animal nutrition, elemental metabolomics
Selenium is an essential trace element in the diet of humans and animals. The efficiency of Se assimilation from diet depends on the form used in the diet. It is a component of more than 30 selenoproteins, which play a significant role in the organism.
Selenoproteins protect cells from damage inflicted by free radicals, the cause of many chronic diseases. They also participate in the metabolism of thyroid hormones, control reproductive functions and exert neuroprotective effects. In addition to its anti-proliferative and anti-inflammatory properties, selenium stimulates the immune system.
Unlike other trace elements, selenium is an element with a very narrow quantitative range of concentrations between deficiency, physiological status, and toxic dose.
Selenium deficiency contributes to pathological changes in animals. Low selenium levels can lead to the development of nutritional muscular dystrophy, exudative diathesis as well as dietary necrotic liver degeneration and mulberry heart disease.
Parturition problems resulting from reduced tension of the muscular layer of the uterus, postparturient paraplegia, placental retention and purulent inflammations of the uterine lining are also attributed to low selenium levels.
Selenium poisoning is rarely encountered, and it most often results from an overdose of selenium supplements. The most common forms of selenosis are chronic selenosis and acute selenosis.
The new roles of Se in antioxidant defenses and cell signaling and recent developments in selenoprotein studies have opened new areas of Se research.
We invite you to contribute your latest research findings or a review article to this Special Issue, which will bring together current research and critical thinking on selenium actions and properties on animal health.
Your contribution can include either in vitro or in vivo studies relating to any of the following topics: Antioxidative activities of selenium; molecular mechanisms of selenium actions in disease prevention; and the role of selenium in signaling, cell metabolism, cell cycle, cellular stress, and animal diseases.
Dr. Evangelos Zoidis
Manuscript Submission Information
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