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Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress

1
Chemistry Laboratory, Department of Food Science and Human Nutrition, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece
2
Department of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece
*
Author to whom correspondence should be addressed.
Antioxidants 2019, 8(7), 216; https://doi.org/10.3390/antiox8070216
Received: 10 June 2019 / Revised: 2 July 2019 / Accepted: 4 July 2019 / Published: 10 July 2019
(This article belongs to the Special Issue Selenium and Animal Health)
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PDF [1626 KB, uploaded 17 July 2019]
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Abstract

Selenium, through incorporation into selenoproteins, is one of the key elements of the antioxidant system. Over the past few years there has been increased interest in exploring those molecular mechanisms in chicken, responsible for the development of this protection system. In more detail, Cd/Pb poisoning and heat stress increase oxidation, mRNA levels of inflammatory proteins, and apoptotic proteins. Selenium seems to enhance the antioxidant status and alleviates these effects via upregulation of antioxidant proteins and other molecular effects. In this review, we analyze avian transcriptome key elements with particular emphasis on interactions with heavy metals and on relation to heat stress. View Full-Text
Keywords: Animal health; heat stress; heavy metals; selenium; selenoprotein; selenotranscriptome Animal health; heat stress; heavy metals; selenium; selenoprotein; selenotranscriptome
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Seremelis, I.; Danezis, G.P.; Pappas, A.C.; Zoidis, E.; Fegeros, K. Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress. Antioxidants 2019, 8, 216.

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