Special Issue "Mitochondrial Function in Health and Disease"
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (31 May 2018).
University of Tampere BioMediTech, Tampere Finland
Interests: neurodegeneration; nervous system; mitochondria; alternative respiratory enzymes; mitochondrial calcium; reactive oxygen species
The mitochondrion is a complex organelle. In addition to being the main source of ATP production in most cells, it hosts and coordinates an array of functions from calcium sequestration and heme synthesis to cell death. Most mitochondrial functions rely on an intact respiratory chain and oxidative phosphorylation. One of the side effects of respiration is the production of reactive oxygen species (ROS) that can be damaging to the cell. At the same time, ROS has emerged as a potential signalling molecule in the cell. Growing awareness of mitochondrial involvement in an increasing number of diseases has led to a steady increase in medical mitochondrial research over the past decades.
This Special Issue aims to publish original research papers and reviews on aspects of mitochondrial function in various disorders ranging from aging and neurodegeneration to diabetes and cardiovascular disorders. It will focus on topics that relate to; how respiratory defects play a role in pathology; the functions of mitochondrial calcium; the influence of ROS on cell death; mitochondrial impact on redox homeostasis; the use of antioxidants for therapy; and agents that promote mitochondrial function as therapeutic targets.
Dr. Kira Holmstrom
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Oxidative phosphorylation
- Oxidative stress
- Cell death
- Cardiovascular disease