Oxidative Stress in Eye Diseases—2nd Edition
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 127
Special Issue Editors
Interests: aging and oxidative stress; antioxidants; reactive oxygen species and molecular signaling; small molecules and therapeutic targets; redox mechanisms and gene regulation
Special Issues, Collections and Topics in MDPI journals
Interests: cataract; posterior capsular opacification; oxidative stress; epithelial-to mesenchymal transition; antioxidant; antiglycation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pioneering research in redox biology has significantly advanced our understanding of how reactive oxygen species (ROS)-induced oxidative stress contributes to aging and age-related ocular diseases. The decline of cellular antioxidant defenses is known to play a key role in the pathogenesis of visual impairments such as glaucoma, age-related macular degeneration, and cataracts; however, despite substantial evidence linking oxidative stress to aging-related blinding conditions, the precise molecular mechanisms driving disease onset remain unclear. Moreover, the reasons for excessive intracellular ROS generation, dysregulation of antioxidant systems, and their connection to distinct forms of cell death—including apoptosis, pyroptosis, and ferroptosis—in the context of ocular pathologies are still not fully elucidated.
Building upon the foundation laid in the first volume, this second Special Issue of Antioxidants aims to further unravel the molecular pathways through which oxidative stress and aging trigger pathological signaling. We encourage submissions that identify key culprit factors involved in the initiation and progression of oxidative stress- and age-related eye diseases, with the goal of informing targeted therapeutic strategies for the management and treatment of these blinding disorders.
Prof. Dr. Dhirendra Pratap Singh
Dr. Eri Kubo
Guest Editors
Manuscript Submission Information
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Keywords
- oxidative stress
- antioxidants
- reactive oxygen species
- redox signaling
- inflammatory cell death
- age-related blinding diseases
- age-related macular degeneration
- retinal disorder
- lens
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Related Special Issue
- Oxidative Stress in Eye Diseases in Antioxidants (7 articles)
