Natural Products for Neuroprotection: Antioxidant Mechanisms and Therapeutic Potential
A Special Issue of Antioxidants (ISSN 2076-3921) belonging to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 15
Editors
Interests: visual science; neuroscience; neurophysiology; retina; photobiomodulation; neurodegeneration; neuroprotection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and age-related retinal degeneration, are characterized by progressive neuronal loss and represent a major global health challenge. Increasing evidence indicates that oxidative stress plays a pivotal role in the onset and progression of these diseases by promoting excessive production of reactive oxygen species (ROS), mitochondrial dysfunction, neuroinflammation, and cellular apoptosis. Consequently, the identification of effective antioxidant strategies has emerged as a promising therapeutic approach for neuroprotection.
Natural products have gained considerable attention due to their ability to modulate multiple molecular pathways involved in neuronal survival. Bioactive compounds derived from plants, such as polyphenols, flavonoids, carotenoids, alkaloids, terpenoids, crocins, and others, exhibit potent antioxidant and anti-inflammatory properties. These compounds can directly scavenge free radicals, enhance endogenous antioxidant defenses through activation of a variety of pathways, preserve mitochondrial function, and regulate cellular signaling mechanisms associated with inflammation and apoptosis.
The topic of this issue aims at exploring the antioxidant mechanisms underlying the neuroprotective effects of natural products (either single molecules or synergistic actions of clearly defined chemical composition of selected batch) and to highlight their therapeutic potential in preventing or slowing neurodegenerative processes. Contributions addressing in vitro and in vivo studies, translational research, novel natural compounds, and innovative delivery strategies are particularly encouraged to advance the development of safe and effective neuroprotective interventions. In addition, a clear and reproducible chemical selection of different natural products paralled to their protective efficacy is highly reccomended.
Prof. Dr. Silvia Bisti
Dr. Ilaria Piano
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurodegenerative diseases
- natural products
- chemical composition
- neuroprotection
- oxidative stress
- neuroinflammation
- translational medicine
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
