Sperm Oxidative Stress and Antioxidant Strategies: From Cryopreservation to Fertility Enhancement
A Special Issue of Antioxidants (ISSN 2076-3921) belonging to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 March 2027 | Viewed by 12
Editor
Interests: animal fertility and reproductive biotechnologies; environmental effects on sperm quality; DNA damage and transgenerational inheritance; sperm metabolism and oxidative stress; enhancement of sperm quality for human assisted reproduction
Special Issue Information
Dear Colleagues,
Reactive oxygen species are both indispensable regulators of sperm function and potent mediators of sperm damage. It is now well established that redox signalling underpins key physiological events, including capacitation, hyperactivation and fertilization, yet even subtle disturbances to this balance can initiate oxidative damage that compromises sperm function, genome integrity and reproductive outcomes. Understanding where the boundary lies between physiological and pathological oxidative stress remains a key challenge in reproductive biology.
This Special Issue of Antioxidants will bring together research exploring the dual roles of oxidative stress throughout the sperm lifespan: from environmental and systemic influences, through epididymal maturation and capacitation, to preservation of sperm function during storage, processing and fertilization. We welcome studies investigating the mechanisms that govern redox homeostasis, the origins and consequences of oxidative injury, biomarkers of oxidative status and targeted antioxidant approaches that preserve or enhance sperm function.
This Special Issue aims to advance a more nuanced understanding of sperm redox biology and foster the development of evidence-based strategies that improve sperm preservation, optimize assisted reproductive technologies and, ultimately, enhance male fertility.
Dr. Aleona Swegen
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- andrology
- spermatozoa
- reproductive technologies
- assisted reproduction
- infertility
- cryopreservation
- IVF
- capacitation
- fertilization
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