Food Proteins and Peptides as Antioxidants: Resource, Extraction, Functional Property and Application

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Extraction and Industrial Applications of Antioxidants".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 719

Special Issue Editors


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Guest Editor
School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China
Interests: food proteins; bioactive components; molecular interaction; structure and function; encapsulation and delivery; alternative proteins
Special Issues, Collections and Topics in MDPI journals
State Key Laboratory of Food Science and Resources, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China
Interests: bioactive components; protein gels; polysaccharides; synergism; biopolymer-based delivery system; in vitro digestion; functional additives and foods
Special Issues, Collections and Topics in MDPI journals
College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China
Interests: proteins; polysaccharides; probiotics; bioactive components; biopolymer-based delivery system; fermentation

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Guest Editor
Department of Food Science and Engineering, College of Chemistry and Environmental Engineering, Shenzhen University, No 1066, Xueyuan Road, Xili, Shenzhen 518071, China
Interests: protein nano assemblies; dairy proteins; in vitro gastrointestinal digestion; protein-polysaccharide composite delivery systems; peptide hydrogels

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Guest Editor Assistant
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 69 Nanyang Drive, Singapore 637459, Singapore
Interests: enzyme catalysis; enzymatic therapy; drug delivery; biosensing; functional nanomaterials; nanofertilizer; plant stress tolerance

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Guest Editor Assistant
Institute of Biomedical Engineering, College of Life Sciences, Qingdao University, Qingdao 266071, China
Interests: protein; bioactive compounds; delivery system; intelligent packaging; interfacial rheology; oxidation stability

Special Issue Information

Dear Colleagues,

Food proteins and their derived peptides serve as both bioactive and functional ingredients in the food industry. Emerging evidence demonstrates that proteins and their derived peptides from both conventional dietary sources (e.g., dairy, eggs, legumes, cereals) and novel alternatives (e.g., algae, insects, microbial proteins) exhibit potent antioxidant capacities. These bioactivities include free radical scavenging (e.g., DPPH/ABTS quenching), metal ion chelation, and modulation of cellular redox signalling pathways (e.g., Nrf2/Keap1 activation), positioning them as sustainable alternatives to synthetic antioxidants. Furthermore, food proteins possess excellent functionalities that facilitate the design and fabrication of edible delivery systems, which can overcome the limitations of natural antioxidants used in food and pharmaceutical industries.

With the growing demand for sustainable and alternative protein sources, there is an urgent need to explore novel resources, optimize extraction technologies, and clarify their nutritional and functional properties for potential uses in food and health fields. This Special Issue aims to compile cutting-edge research and reviews on the discovery, processing, characterization, and utilization of food proteins with high-performance functionality and antioxidant activity from conventional and unconventional sources. We welcome contributions highlighting interdisciplinary studies that bridge molecular insights with innovations, addressing challenges in sustainable protein utilization, novel extraction methods, and tailored functionalities for health and industry.

Prof. Dr. Li Liang
Dr. Hao Cheng
Dr. Wusigale
Dr. Muhammad Aslam Khan
Guest Editors

Dr. Di Li
Dr. Xin Yin
Guest Editor Assistants

Manuscript Submission Information

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Keywords

  • protein resources
  • protein extraction and characterization
  • functional properties of proteins
  • antioxidant activity
  • protein application

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Published Papers (1 paper)

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Research

17 pages, 1651 KB  
Article
The Role of Inulin in Maintaining Antioxidant Capacity and Enzymatic Activities of Jerusalem Artichoke (Helianthus tuberosus L.) Cultivars During Cold Storage
by Yuwen Mu, Bohua Zhang, Shiqi Lv, Fencan Li and Changming Zhao
Antioxidants 2025, 14(9), 1109; https://doi.org/10.3390/antiox14091109 - 12 Sep 2025
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Abstract
Jerusalem artichoke (Helianthus tuberosus L.) is valued for its high inulin content and adaptability to marginal lands. This study investigated the changes in inulin content, antioxidant capacity, polyphenol concentrations, and enzymatic activities of eight cultivars during 60 days of cold storage. Inulin [...] Read more.
Jerusalem artichoke (Helianthus tuberosus L.) is valued for its high inulin content and adaptability to marginal lands. This study investigated the changes in inulin content, antioxidant capacity, polyphenol concentrations, and enzymatic activities of eight cultivars during 60 days of cold storage. Inulin levels ranged from 582.43 g/kg (LZJ006) to 809.70 g/kg (LZJ055), with LZJ047 maintaining the highest content throughout storage. The antioxidant potential, as measured by ferric reducing antioxidant power (FRAP) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, declined across all cultivars, correlating with the reduction in inulin content. The polyphenol content varied significantly, with LZJ119 having 2.17 times more than LZJ010. POD activity increased, while catalase (CAT) and superoxide dismutase (SOD) activities fluctuated during the storage period. Hierarchical Cluster Analysis identified three distinct antioxidant clusters, revealing significant correlations between inulin content and key antioxidant parameters (CAT, FRAP, DPPH). These findings highlight the pivotal role of inulin in preserving the antioxidant system and bioactive properties of Jerusalem artichoke tubers during extended cold storage, providing valuable insights for post-harvest management and cultivar selection. Full article
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