Antioxidant Response in Aquatic Animals, 2nd Edition

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: 31 August 2026 | Viewed by 672

Special Issue Editor


E-Mail Website
Guest Editor
Unidad Multidisciplinaria de Docencia e Investigación, Facultad de Ciencias, UNAM, Puerto de Abrigo s/n, Sisal 97356, Mexico
Interests: antioxidant system and nutrition and culture
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Reactive oxygen species (ROS), which are produced via mitochondrial respiration in all tissues in aquatic organisms, are deactivated by the antioxidant enzyme system, which constitutes superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT), among other enzymes. This system is responsible for protecting cell membranes and preventing lipid peroxidation.

This defense is of paramount importance in tissues with high metabolic and exchange activity. For instance, the gills, the primary sites for gas exchange, osmoregulation, and ammonia excretion, are particularly susceptible to oxidative stress. Antioxidant capacity is critical for protecting tissue function and overall organismal health.

Following the success of our first edition (available at: https://www.mdpi.com/journal/antioxidants/special_issues/FT2189OQ5Q), we are pleased to announce the launch of this Second Edition. We continue to invite the submission of original research articles and comprehensive reviews that deepen our understanding of antioxidant mechanisms in aquatic animals.

Articles pertaining to invertebrates, such as shrimp and mollusks, and vertebrates, such as freshwater and marine fish, are welcome. This Special Issue covers both in vitro and in vivo studies related to any of the following topics: nutrition; immunology and physiology related to the presence of reactive species scavenging radicals or the modulation of their production; antioxidant defense systems and pathways; inflammation; mitochondrial dysfunction; cell death; and differential expression in the antioxidant system.

Prof. Dr. Martha Gabriela Gaxiola-Cortes
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidant system
  • respiration
  • nutrition
  • culture
  • fish
  • aquatic animals
  • reactive oxygen species (ROS)
  • superoxide dismutase (SOD)

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

18 pages, 3167 KB  
Article
Pten-Mediated Antioxidant Response Alleviates Hydrogen Peroxide-Induced Oxidative Damage in Tilapia Muscle
by Jianxiang Chen, Pao Xu, Miaomiao Xue, Jiyan He, Huaishun Shen, Hongxia Li and Changyou Song
Antioxidants 2026, 15(4), 499; https://doi.org/10.3390/antiox15040499 - 17 Apr 2026
Viewed by 431
Abstract
The mechanisms underlying hydrogen peroxide (HP)-induced oxidative stress damage in the muscle of Nile tilapia (Oreochromis niloticus) remain poorly understood. In this study, an oxidative stress model was established through 2 mM HP exposure for 4 weeks to elucidate the effects [...] Read more.
The mechanisms underlying hydrogen peroxide (HP)-induced oxidative stress damage in the muscle of Nile tilapia (Oreochromis niloticus) remain poorly understood. In this study, an oxidative stress model was established through 2 mM HP exposure for 4 weeks to elucidate the effects of oxidative stress on tilapia muscle and regulatory mechanisms. The results demonstrated that prolonged oxidative stress inhibited the antioxidant response in tilapia muscle and significantly reduced body weight. Concurrently, oxidative stress downregulated the gene expression of muscle proliferation and development, leading to a loss of muscle mass and the deterioration of muscle texture. Furthermore, oxidative stress altered muscle cell fate and exacerbated inflammatory responses. Further transcriptomic analysis revealed that Pten played a critical regulatory role in the muscle antioxidant response and growth. Mechanistically, activation of Pten ameliorated antioxidant capacity and promoted cell proliferation. In conclusion, HP-mediated oxidative stress significantly inhibited muscle proliferation and development, while targeted regulation of Pten effectively alleviated the suppression of muscle antioxidant capacity and cell proliferation. This study provided a theoretical basis for the prevention and control of oxidative stress injury in tilapia aquaculture. Full article
(This article belongs to the Special Issue Antioxidant Response in Aquatic Animals, 2nd Edition)
Show Figures

Figure 1

Back to TopTop