Advances in Antibiotic Synergy and Combination Therapy for Multidrug-Resistant Infections
Special Issue Editor
Interests: antimicrobial resistance; multidrug resistant Gram-negatives; resistance mechanims; PK/PD studies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to announce a forthcoming Special Issue titled “Advances in Antibiotic Synergy and Combination Therapy for Multidrug-Resistant Infections,” and we invite researchers, clinicians, and industry experts to contribute original research articles, reviews, and short communications that explore innovative strategies to combat antimicrobial resistance through combination therapy. As multidrug-resistant (MDR) pathogens continue to pose a critical global health threat, this issue aims to highlight recent progress in identifying synergistic antibiotic combinations, understanding their mechanisms of action, and translating in vitro findings into clinical success. We are particularly interested in studies involving novel antibiotic pairings, phage–antibiotic synergy, adjuvant therapies, pharmacokinetic/pharmacodynamic modeling, and clinical outcomes of combination regimens in MDR and XDR infections.
This Special Issue seeks to provide a comprehensive platform for advancing both the science and clinical application of combination antimicrobial therapy. Submissions addressing the rational design of synergistic therapies, overcoming resistance mechanisms, or integrating diagnostic and stewardship tools are especially welcome. We encourage contributions from interdisciplinary teams and international collaborators that can provide new insights into optimizing treatment regimens for resistant infections across diverse settings. Through this collection, we aim to foster knowledge exchange and stimulate future research that can lead to more effective and sustainable treatment strategies against the growing challenge of antimicrobial resistance.
Dr. Vasiliki Koumaki
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- multidrug-resistant (MDR)
- synergistic antibiotic combinations
- novel antibiotic pairings
- phage–antibiotic synergy
- pharmacokinetic/pharmacodynamic modeling
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