Special Issue "New Approaches in Antimicrobial Drug Discovery and Design"

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Mechanisms of Antibiotic Action".

Deadline for manuscript submissions: 30 September 2023 | Viewed by 118

Special Issue Editor

Department of Genetics, Faculty of Biology, Sofia University St. Kliment Ohridski, 8 Dragan Tzankov Blvd, 1164 Sofia, Bulgaria
Interests: ribozymes; riboswitches; bioinformatics; biosensors; microfluidics; DNA/RNA computing; RNA synthetic biology; rational drug design

Special Issue Information

Dear Colleagues,

The rise of multi-drug-resistant human pathogenic bacteria found in many infectious diseases worldwide is a global problem recognized by the World Health Organization. To confront this global health threat, we must develop novel strategies for improved antibacterial drug development that are prompt, accurate, and consequently more efficient. Such approaches can be based on genome-wide bioinformatics analyses and systems biology for the in silico evaluation of new targets for antibacterial drug development. In addition, various synthetic biology tools can be employed to rationalize new antibacterial drug agents. Therefore, the main subject of this Special Issue includes novel approaches for antibacterial drug development based on novel drug targets, mechanisms of action, rational drug design, in silico drug target evaluation using bioinformatics and AI-based methods, etc. 

Prof. Dr. Robert Penchovsky
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • rational drug design
  • multi-drug resistant human pathogenic bacteria
  • new antibiotics
  • antibacterial drugs
  • antibacterial drug targets
  • in silico drug target evaluation

Published Papers

This special issue is now open for submission.
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