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Applications and Impacts of Nanotechnology in Animals

A Special Issue of Animals (ISSN 2076-2615) belonging to the section "Animal Reproduction".

Deadline for manuscript submissions: 31 March 2027 | Viewed by 1093

Editors


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Guest Editor
Department of Physiological Sciences, Institute of Biological Sciences, Campus Universitário Darcy Ribeiro, Brasilia 70910-900, DF, Brazil
Interests: nanocontraception; ovarian tissue cryopreservation; nanowarming; fertility preservation; germ cells ultrastructure
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Guest Editor Assistant
Laboratory of Animal Reproduction, Department of Physiological Sciences, Institute of Biological Sciences, Campus Universitário Darcy Ribeiro, Brasilia 70910-900, DF, Brazil
Interests: nanomaterials toxicity; nanomaterial biodistribution; spermatogenesis; male infertility; nanoparticle-mediated hyperthermia; nanocontraception

Special Issue Information

Dear Colleagues,

Nanotechnology has been the focus of numerous studies in recent years. Nanotechnology has emerged as a new approach for diagnosis and treatment of many animal diseases as well as a tool in animal production and reproduction. On the other hand, residual nanomaterials in the environment may pose risks to animal health and welfare.

The Special Issue, “Applications and Impacts of Nanotechnology in Animals”, aims to share information and to promote and improve new and existing knowledge about the use of nanomaterials and nanotechnology in animal reproduction, production, nutrition, health management, and veterinary medicine. Studies may include companion, farm, and wild animals. We welcome the submission of reviews and original contributions addressing topics including, but not limited to, the following:

  • Nanotechnology in animal reproduction
  • Nanotechnology in animal production
  • Nanotechnological strategies in animal nutrition
  • Nanotechnology in veterinary medicine (diagnosis and treatment)
  • Nanotechnological approaches to animals’ health management
  • Toxicity of nanomaterials to animals

Prof. Dr. Carolina Madeira Lucci
Guest Editor

Dr. Juliana Lis Mendes Brito
Guest Editor Assistant 

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanomaterials
  • nanotheragnosis
  • nanotechnology
  • nanotoxicology
  • nanoplastic

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Published Papers (1 paper)

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Research

27 pages, 1920 KB  
Article
Ovarian Function, Hormonal, Metabolic, Oxidative Stress, and Gene Expression Biomarker Responses of Holstein Heifers Under Heat Stress Conditions to a Reduced Dose of Nanofabricated GnRH Analog Within the Ovsynch Protocol
by Eman M. Hassanein, Ottó Szenci, Rezk S. Ghallab, Ahmed A. Saleh, Mariam S. Abdelfattah, Ebrahim F. Zayed, Mohamed F. Kilany, Zoltán Szelényi and Abdelghany A. El-Shereif
Animals 2026, 16(14), 2163; https://doi.org/10.3390/ani16142163 - 12 Jul 2026
Viewed by 419
Abstract
This study investigated the efficacy of a modified Ovsynch (MOVS) protocol incorporating a 50% reduced dose of a gonadotropin-releasing hormone analog (GnRHa) conjugated with chitosan nanoparticles. Thirty-two Holstein heifers under heat-stress (HS) conditions were randomly assigned to either a standard Ovsynch [...] Read more.
This study investigated the efficacy of a modified Ovsynch (MOVS) protocol incorporating a 50% reduced dose of a gonadotropin-releasing hormone analog (GnRHa) conjugated with chitosan nanoparticles. Thirty-two Holstein heifers under heat-stress (HS) conditions were randomly assigned to either a standard Ovsynch (SOVS) or MOVS protocol (n = 16/group). Ovarian dynamics were monitored across the protocol days (D0, D3, D7, D9, D14, and D19). Hormonal profiles, metabolic and oxidative markers, and mRNA expressions of folliculogenesis- and apoptosis-related genes were evaluated. Both protocols improved follicular recruitment (p > 0.05). However, the MOVS significantly enhanced the dominant follicle (DF) diameter on D9 (p < 0.001). On D14 and D19, CL diameters were larger in the MOVS group (p < 0.001). These findings were associated with significantly high estradiol (E2) concentrations on D9 (p < 0.05) and progesterone (P4) concentrations on D19 (p < 0.05). Metabolic and oxidative stress markers were increased in MOVS-treated heifers, while antioxidant markers were also improved (p < 0.05). At the molecular level, the MOVS numerically upregulated the expression of folliculogenesis-related genes (BMP15, GDF9, LHR, FSHR, and IGF-1R) and an anti-apoptotic gene (BCL2) in peripheral blood (p > 0.05). In conclusion, the MOVS protocol achieved a 50% reduction in GnRHa dose while improving ovarian, endocrine, and reproductive physiological indicators, suggesting a promising strategy for optimizing synchronization in heifers under HS conditions. Full article
(This article belongs to the Special Issue Applications and Impacts of Nanotechnology in Animals)
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