Special Issue "Biophysical Micro- and Nano-Actuators"
A special issue of Actuators (ISSN 2076-0825).
Deadline for manuscript submissions: closed (31 October 2015) | Viewed by 13560
Interests: biologically sensors and actuators; CMOS biosensors; integrated microfluidic microelectronic systems
Special Issues, Collections and Topics in MDPI journals
Special Issue in Sensors: Integrated Microfluidic CMOS (imCMOS) Sensors and Actuators for Life Science Applications
Special Issue in Sensors: Hybrid Microfluidic/Integrated Sensors for Life Science Applications
Special Issue in Micromachines: Biologically Inspired Sensor and Actuator (BioSA) Platforms
Special Issue in Biosensors: Biosensors Applications Based on Field-Effect Transistors Technologies
Special Issue in Bioengineering: COVID-19 Diagnostic Strategies: Lessons for Current and Future Pandemic Threats
Special Issue in Micromachines: Advanced FET Based Sensors for Life Science Applications
Biological actuations are defined as physical stimulation (e.g., mechanical, electrical, etc.) techniques to control or change the cell or molecular activities. Recent advances of micro- and nanotechnologies have received significant attention from researchers for the development of novel biological actuation techniques for various in vitro and in vivo life science applications, including, but not limited to, rare cell isolation, separation of macromolecules, such as DNA, RNA, and proteins from a sample, cell Lysis, precise localization of cells for microscopic purposes, enhancing the sensitivity of biosensors by manipulating the labeled cells/molecules toward recognition element (e.g., Antibody, DNA, Aptemer), opening the blood brain barrier (BBB) for drug delivery, creating pores in the cell membrane for molecular transfection, cell stimulation using various physical factors for stem cell differentiation and tissue engineering, and neural cell stimulation. To date, many biophysical techniques, such as Dielectrophoresis (DEP), Electrophoresis, Electroporation, magnetic cellular manipulation using micro-beads or magnetic nano-particles, optical tweezers, patch-clamping methods, MRI-guided nanoparticles for crossing BBB, and ultrasonic techniques for crossing BBB have been applied.
This Special Issue targets the recent progress, including simulation, modeling and experimental works, on the following topics:
- DEP manipulation for cell separation, levitation, trapping, etc.
- Magnetic manipulation using magnetic/super-paramagnetic micro-beads or nano-particles
- Ultrasound manipulation for cell separation
- Ultrasound manipulation for opening BBB
- MRI-guided drug delivery toward the target tissue in the body
- Electroporation to deliver small or large molecules into cells
- Mechanical stimulation cells for tissue engineering
- Electrical Excitation of neural cells for neuroscience studies
- Electrophoresis for molecular separation in microfluidic devices
- Optogenetic actuators for controlling cellular activities
- Thermal Stimulation of cells
- Other biological actuation techniques
Dr. Ebrahim Ghafar-Zadeh
Manuscript Submission Information
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