The “Molecular Genetics and Genetic Diseases” Section covers the basic and translational aspects of human genetic disease and genomic research, from fundamental molecular investigations to preclinical animal models. In particular, this Section aims to facilitate the rapid publication of innovative research encompassing the genetic basis of human health and disease, as well as the treatment of genetic disorders and heritable or acquired cancers. We welcome submissions that apply new and emerging technologies in the fields of genomics, transcriptomics, and bioinformatic tools to advance knowledge in human genetic diseases.

1. “Sensitivity Analysis for Survival Prognostic Prediction with Gene Selection: A Copula Method for Dependent Censoring”
by Chih-Tung Yeh, Gen-Yih Liao and Takeshi Emura
Biomedicines 2023, 11(3), 797; https://doi.org/10.3390/biomedicines11030797
Available online: https://www.mdpi.com/2227-9059/11/3/797

2. “Targeted DNA Demethylation: Vectors, Effectors and Perspectives”
by Naohiro Yano and Alexey V. Fedulov
Biomedicines 2023, 11(5), 1334; https://doi.org/10.3390/biomedicines11051334
Available online: https://www.mdpi.com/2227-9059/11/5/1334

3. “Increasing Specificity of Targeted DNA Methylation Editing by Non-Enzymatic CRISPR/dCas9-Based Steric Hindrance”
by Daniel M. Sapozhnikov and Moshe Szyf
Biomedicines 2023, 11(5), 1238; https://doi.org/10.3390/biomedicines11051238
Available online: https://www.mdpi.com/2227-9059/11/5/1238

4. “The Enigmatic Genetic Landscape of Hereditary Hearing Loss: A Multistep Diagnostic Strategy in the Italian Population”
by Beatrice Spedicati, Aurora Santin, Giuseppe Giovanni Nardone, Elisa Rubinato, Stefania Lenarduzzi, Claudio Graziano, Livia Garavelli, Sara Miccoli, Stefania Bigoni, Anna Morgan et al.
Biomedicines 2023, 11(3), 703; https://doi.org/10.3390/biomedicines11030703
Available online: https://www.mdpi.com/2227-9059/11/3/703

5. “Recent Therapeutic Progress and Future Perspectives for the Treatment of Hearing Loss”
by Joey Lye, Derek S. Delaney, Fiona K. Leith, Varda S. Sardesai, Samuel McLenachan, Fred K. Chen, Marcus D. Atlas and Elaine Y. M. Wong
Biomedicines 2023, 11(12), 3347; https://doi.org/10.3390/biomedicines11123347
Available online: https://www.mdpi.com/2227-9059/11/12/3347

6. “Clinical and Molecular Aspects Associated with Defects in the Transcription Factor POU3F4: A Review”
by Emanuele Bernardinelli, Florian Huber, Sebastian Roesch and Silvia Dossena
Biomedicines 2023, 11(6), 1695; https://doi.org/10.3390/biomedicines11061695
Available online: https://www.mdpi.com/2227-9059/11/6/1695

7. “CT-Based Radiomics to Predict KRAS Mutation in CRC Patients Using a Machine Learning Algorithm: A Retrospective Study”
by Jacobo Porto-Álvarez, Eva Cernadas, Rebeca Aldaz Martínez, Manuel Fernández-Delgado, Emilio Huelga Zapico, Víctor González-Castro, Sandra Baleato-González, Roberto García-Figueiras, J Ramon Antúnez-López and Miguel Souto-Bayarri
Biomedicines 2023, 11(8), 2144; https://doi.org/10.3390/biomedicines11082144
Available online: https://www.mdpi.com/2227-9059/11/8/2144

8. “Panoramic on Epigenetics in Coronary Artery Disease and the Approach of Personalized Medicine”
by Marcello Bergonzini, Francesco Loreni, Antonio Lio, Marco Russo, Guglielmo Saitto, Antonio Cammardella, Francesco Irace, Corrado Tramontin, Massimo Chello, Mario Lusini et al.
Biomedicines 2023, 11(10), 2864; https://doi.org/10.3390/biomedicines11102864
Available online: https://www.mdpi.com/2227-9059/11/10/2864

9. “Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPD”
by Ana I. Hernandez Cordero, Xuan Li, Chen Xi Yang, Julia Yang, Julia L. MacIsaac, Kristy Dever, Michael S. Kobor, Stephen Milne, Stephan F. van Eeden, Tawimas Shaipanich et al.
Biomedicines 2023, 11(1), 134; https://doi.org/10.3390/biomedicines11010134
Available online: https://www.mdpi.com/2227-9059/11/1/134

10. “Chronic Pelvic Pain, Vulvar Pain Disorders, and Proteomics Profiles: New Discoveries, New Hopes”
by Chiara Di Tucci and Ludovico Muzii
Biomedicines 2024, 12(1), 1; https://doi.org/10.3390/biomedicines12010001
Available online: https://www.mdpi.com/2227-9059/12/1/1

We would like to take this opportunity to thank all the research groups that have submitted their research to Biomedicines (ISSN: 2227-9059). We would appreciate it if you could circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link: https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Launching a Special Issue:
You have the opportunity to propose hot topics and edit a Special Issue together with experts in the field.

Joining the Editorial Board:
If you are an active researcher in the fields of mineral processing and extractive metallurgy and are interested in joining the Editorial Board, please do not hesitate to get in touch (biomedicines@mdpi.com).

Biomedicines Editorial Office