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Gout, Urate, and Crystal Deposition Disease, Volume 3, Issue 1

2025 March - 4 articles

Cover Story: China now has the highest number of gout cases globally; its prevalence is increasing with earlier onset and rising numbers of cases among adolescents. This Review summarizes a decade of epidemiology, clinical, and research advances in China, including hyperuricemia classification-based urate-lowering therapy, urine alkalization strategies, and genetic insights into drug response. We also explore the emerging roles of metabolomics and gut microbiota in non-invasive diagnosis and precision management. View this paper
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Articles (4)

  • Review
  • Open Access
1 Citations
3,278 Views
17 Pages

Convergence of Psoriatic Arthritis and Hyperuricemia: A Review of Emerging Data from This New Concept Called “Psout”

  • Renaud Felten,
  • Laura Widawski,
  • Pierre-Marie Duret,
  • Lionel Spielmann and
  • Laurrent Messer

This review examines the concept of “psout”, an overlap syndrome of hyperuricemic psoriatic arthritis (HU-PsA) and co-existing gout and PsA. The manuscript explores its epidemiology, pathophysiology, clinical implications, and treatment s...

  • Perspective
  • Open Access
5,789 Views
7 Pages

Treat to Target in Gout Management: A Critical Reappraisal of Current Strategies

  • Anusha Moses,
  • Martijn Oude Voshaar,
  • Mart van de Laar and
  • Tim L. Th. Jansen

Gout management strategies remain a topic of debate, particularly regarding the efficacy of treat-to-target (T2T) and treat-to-avoid-symptoms (T2S) approaches. T2T, endorsed by major rheumatology societies, involves systematic serum urate (sUA) monit...

  • Perspective
  • Open Access
2 Citations
5,459 Views
8 Pages

Can Urate Lowering Therapy Be Stopped in Gout? Rationale and Design of Two Large Randomised Trials

  • Pascal Richette,
  • Marcel Flendrie,
  • Leo A. B. Joosten and
  • Noortje van Herwaarden

Lifelong urate-lowering therapy (ULT) is recommended for gout to prevent flares and urate deposition. However, concerns about its adherence, long-term side effects, and the necessity of continuous treatment after achieving remission raise critical qu...

  • Review
  • Open Access
7 Citations
8,347 Views
21 Pages

Gout in China

  • Aichang Ji,
  • Zibin Tian,
  • Yongyong Shi,
  • Riku Takei,
  • Shun-Jen Chang,
  • Ronald M. L. Yip,
  • Huiyong Yin and
  • Changgui Li

Gout is a common inflammatory joint disease in China. In recent years, the prevalence of gout in China has been increasing and the onset age of gout has been trending younger. The common risk factors for gout in China include hyperuricemia, age, sex,...

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Gout Urate Cryst. Depos. Dis. - ISSN 2813-4583