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Osteology, Volume 4, Issue 1

2024 March - 3 articles

Cover Story: Gene therapy is gaining traction as an effective treatment for several deleterious disorders by delivering genetic material using viral or non-viral vectors to correct mutated genes. Research in the field focuses primarily on the treatment of cancers; however, it shows great promise for treating diseases related to pediatric orthopedics. This review aims to describe gene therapy’s application, efficacy and safety in pediatric orthopedics. This paper will examine common pediatric orthopedic disorders including Duchenne muscular dystrophy, osteogenesis imperfecta, spinal muscular atrophy and osteosarcoma. As a whole, gene therapy is rapidly advancing in the field of pediatric orthopedics; however, further research is crucial in continuing and spreading these advancements and for the treatment of other debilitating pediatric-related orthopedic disorders. View this paper

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Articles (3)

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Review

3,135 Views

12 Pages

Gene Therapy in Pediatric Orthopedics

Emmanuel Olaonipekun,
Anthony Lisyansky,
Robin Olaonipekun,
Bouchra Ghania Merabia,
Karim Gaber and
Waleed Kishta

Osteology2024, 4(1), 33-44;https://doi.org/10.3390/osteology4010003

6 March 2024

Gene therapy is gaining traction as an effective treatment for several deleterious disorders by delivering genetic material using viral or non-viral vectors to correct mutated genes. Research in the field focuses primarily on the treatment of cancers...

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Review

1 Citations

5,328 Views

22 Pages

Sixty Years of Innovation in Biomechanical Orthognathic Surgery: The State of the Art and Future Directions

Carlos Aurelio Andreucci

Osteology2024, 4(1), 11-32;https://doi.org/10.3390/osteology4010002

11 February 2024

Craniofacial surgery is proposed and performed for a variety of reasons, ranging from congenital or acquired malformations to emotional disorders and parafunctions of the masticatory, respiratory, auditory, and visual systems. Surgery of the mandible...

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Case Report

1 Citations

4,892 Views

10 Pages

Mandibular Fracture following Dental Implant Protocol: Clinical Report and One-Year Follow-Up

Calber Artur Andreucci,
Murillo Martins and
Carlos Aurelio Andreucci

Osteology2024, 4(1), 1-10;https://doi.org/10.3390/osteology4010001

26 January 2024

Bone fractures following mandibular dental implant protocols associated with diagnosed osteoporosis are rare in the literature. We present a case in which a 55-year-old male patient with no previous medical history presented to the emergency departme...

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Osteology - ISSN 2673-4036

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