Correlation between Helicobacter pylori Infection and Gastric Atrophy Examined in the Sera of Mongolian People
Abstract
:1. Introduction
2. Results
2.1. Detection of Anti-H. pylori Antibodies in the Sera of Mongolian People by Two Different ELISA Kits
2.2. Detection of Anti-CagA Antibodies in the Sera of Mongolian People
2.3. Relationship between the Ratio of Pepsinogen 1/2 and H. pylori Infection
3. Discussion
4. Materials and Methods
4.1. Study Population
4.2. Detection of Antibodies against H. pylori, CagA, and Pepsinogens in Serum Specimens
4.3. Ethics
4.4. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Age Group | Gender | Total | ||
---|---|---|---|---|
Female | Male | |||
10–15 | 10–19 | 137 | 102 | 239 |
16–19 | 29 | 27 | 56 | |
20–29 | 20–39 | 100 | 55 | 155 |
30–39 | 54 | 33 | 87 | |
40–49 | Over 40 | 38 | 24 | 62 |
50–59 | 4 | 2 | 6 | |
Over 60 | 2 | 3 | 5 | |
Total | 364 | 246 | 610 | |
Mean age | 22.9 |
Age Group | Anti-H. pylori IgG Biohit | Anti-H. pylori IgG E-plate | ||||
---|---|---|---|---|---|---|
Negative | Positive | Percent | Negative | Positive | Percent | |
10–19 | 34 | 261 | 88.47% | 107 | 188 | 63.72% |
20–39 | 13 | 229 | 94.63% | 80 | 162 | 66.94% |
Over 40 | 3 | 70 | 95.89% | 35 | 38 | 52.05% |
Total | 50 | 560 | 91.8% | 222 | 388 | 63.6% |
Japanese | Anti-CagA Antibody | Mongolians | Anti-CagA Antibody | ||||
---|---|---|---|---|---|---|---|
Positive | Negative | Positive | Negative | ||||
Biohit | Positive | 28 | 1 | Biohit | Positive | 500 | 60 |
Negative | 0 | 41 | Negative | 6 | 44 | ||
E-plate | Positive | 27 | 0 | E-plate | Positive | 367 | 21 |
Negative | 1 | 42 | Negative | 139 | 83 |
H. pylori | Pepsinogen Ratio | Age Group | Total | Total Positive Cases | ||
---|---|---|---|---|---|---|
10–19 | 20–39 | Over 40 | ||||
Positive | <3 | 8 | 26 | 13 | 47 | 560 |
<5 | 28 | 91 | 38 | 157 | ||
Negative | <3 | 0 | 2 | 2 | 4 | |
<5 | 1 | 4 | 2 | 7 |
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Amgalanbaatar, A.; Shimomura, H.; Sugano, K.; Bira, T.-O.; Okamoto, H.; Hirai, Y. Correlation between Helicobacter pylori Infection and Gastric Atrophy Examined in the Sera of Mongolian People. Gastrointest. Disord. 2019, 1, 241-252. https://doi.org/10.3390/gidisord1020019
Amgalanbaatar A, Shimomura H, Sugano K, Bira T-O, Okamoto H, Hirai Y. Correlation between Helicobacter pylori Infection and Gastric Atrophy Examined in the Sera of Mongolian People. Gastrointestinal Disorders. 2019; 1(2):241-252. https://doi.org/10.3390/gidisord1020019
Chicago/Turabian StyleAmgalanbaatar, Avarzed, Hirofumi Shimomura, Kentaro Sugano, Tsatsralt-Od Bira, Hiroaki Okamoto, and Yoshikazu Hirai. 2019. "Correlation between Helicobacter pylori Infection and Gastric Atrophy Examined in the Sera of Mongolian People" Gastrointestinal Disorders 1, no. 2: 241-252. https://doi.org/10.3390/gidisord1020019
APA StyleAmgalanbaatar, A., Shimomura, H., Sugano, K., Bira, T. -O., Okamoto, H., & Hirai, Y. (2019). Correlation between Helicobacter pylori Infection and Gastric Atrophy Examined in the Sera of Mongolian People. Gastrointestinal Disorders, 1(2), 241-252. https://doi.org/10.3390/gidisord1020019