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Open AccessCase Report

Embolization of Bio-Alcamid Gluteal Injections in a Female Patient with Patent Foramen Ovale Leading to ARDS and Embolic Stroke

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Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA
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School of Pharmacy, Hampton University, Hampton, VA 23668, USA
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Author to whom correspondence should be addressed.
Reports 2019, 2(4), 23; https://doi.org/10.3390/reports2040023
Received: 22 July 2019 / Revised: 5 September 2019 / Accepted: 24 September 2019 / Published: 26 September 2019
Bio-Alcamid is a non-FDA approved permanent dermal filler with a few known adverse effects including granuloma formation at injection site, skin infections, abscess and painful inflammation. Embolization of Bio-Alcamid has not been reported and likely represents a very rare complication. We present the case of a thirty-one-year-old female who presents with cough, dyspnea, hemoptysis, fever, and pleuritic chest pain several hours after receiving Bio-Alcamid gluteal injections. The patient’s symptoms progress rapidly and, within three days, she develops acute respiratory failure requiring intubation. A chest x-ray consistent with acute respiratory distress syndrome (ARDS) is viewed. Concurrently, a 2D echocardiogram reveals a patent foramen ovale (PFO) and severe pulmonary hypertension. Five weeks after initial presentation to the emergency department, the patient demonstrates flaccid quadriplegia, is poorly responsive when sedation is held, and her CT scan of the brain showed multifocal infarcts involving bilateral cerebral hemispheres. A CT of the abdomen reveals renal and splenic infarcts. This case study presents a rare complication of a nonbiodegradable dermal filler, Bio-Alcamid. View Full-Text
Keywords: bio-alcamid; dermal filler; acute respiratory distress syndrome; embolic stroke bio-alcamid; dermal filler; acute respiratory distress syndrome; embolic stroke
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MDPI and ACS Style

Bolduc, J.; Abdalla, B.; Choudhry, M.; Danial, M.; Rizvi, S.A.A. Embolization of Bio-Alcamid Gluteal Injections in a Female Patient with Patent Foramen Ovale Leading to ARDS and Embolic Stroke. Reports 2019, 2, 23.

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