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Open AccessCase Report

An Unusual Case of Vomiting Caused by Myeloid Sarcoma

1
Hematology Department, Royal Blackburn Hospital, Haslingden Road, Blackburn, Lancashire BB2 3HH, UK
2
Gastroenterology Department, Royal Blackburn Hospital, Haslingden Road, Blackburn, Lancashire BB2 3HH, UK
3
Radiology Department, Royal Blackburn Hospital, Haslingden Road, Blackburn, Lancashire BB2 3HH, UK
4
Pathology Department, Royal Blackburn Hospital, Haslingden Road, Blackburn, Lancashire BB2 3HH, UK
*
Author to whom correspondence should be addressed.
Received: 23 November 2018 / Revised: 25 December 2018 / Accepted: 3 January 2019 / Published: 8 January 2019
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Abstract

Myeloid sarcoma is an extramedullary mass consisting of myeloblasts that may present simultaneously or precede a bone marrow disorder. It has been reported to occur without a known preexisting diagnosis of acute leukemia, myelodysplastic syndrome or a myeloproliferative neoplasm and this is known as primary myeloid sarcoma. Here, we report a case of an 80-year-old male who presented with intermittent vomiting and significant weight loss for 3 months. The imaging and histological findings were consistent with a mesenteric myeloid sarcoma encasing the coeliac trunk and superior mesenteric artery, abutting and obstructing the proximal small bowel, causing subacute bowel obstruction. Systemic chemotherapy with low dose cytarabine achieved a reduction in the size of myeloid sarcoma and improved patient’s symptomatology but unfortunately our patient succumbed to progression 11 months later. View Full-Text
Keywords: myeloid sarcoma; extra medullary tumor; acute myeloid leukemia myeloid sarcoma; extra medullary tumor; acute myeloid leukemia
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Goodoory, V.C.; Triantafyllopoulou, D.; Gkikas, I.; Alani, F.; Bin, A.A.; Mellor, S.; Adiyodi, J.; Sahasrabudhe, N.; Saxton, M.; Cowburn, H. An Unusual Case of Vomiting Caused by Myeloid Sarcoma. Reports 2019, 2, 2.

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