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Clinical and Translational Neuroscience, Volume 9, Issue 1

March 2025 - 19 articles

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Articles (19)

  • Review
  • Open Access
1 Citations
3,383 Views
10 Pages

Multiple sclerosis (MS) is a chronic autoimmune-mediated neurodegenerative disease that affects young adults. The diagnosis of MS currently based on the McDonald criteria, which based on four core principles: the presence of a symptomatic demyelinati...

  • Perspective
  • Open Access
4 Citations
3,843 Views
16 Pages

The study of brain disorders has long been central to both neurology and psychiatry, with these two disciplines evolving as distinct yet deeply interconnected fields. In fact, these specialties often share overlapping symptoms, neural pathways, and t...

  • Review
  • Open Access
2 Citations
2,623 Views
16 Pages

Clot Composition and Pre-Interventional Radiological Characterization for Better Prognosis and Potential Choice of Treatment in Acute Ischemic Strokes

  • Samuel Tell Gurary,
  • Daniela LaGrange,
  • Daniele Botta,
  • Paolo Machi,
  • Isabel Wanke,
  • Felix Tobias Kurz and
  • Karl-Olof Lovblad

Acute ischemic stroke (AIS) remains a critical concern in clinical practice, with significant implications for patient outcomes and healthcare costs. This review highlights the role of clot composition in AIS, emphasizing the clinical relevance of ra...

  • Review
  • Open Access
2,655 Views
16 Pages

Headache and Facial Pain in Multiple Sclerosis: A Narrative Review

  • Lukasz Kolakowski,
  • Katarina Alexandra Ebner and
  • Athina Papadopoulou

Headache and facial pain syndromes are frequently observed in people with multiple sclerosis (MS), often affecting young adults during pivotal stages of their lives. These conditions can disrupt their ability to work, maintain relationships, and enga...

  • Article
  • Open Access
1 Citations
2,139 Views
12 Pages

Objective Sleep–Wake Findings in Patients with Post-COVID-19 Syndrome, Fatigue and Excessive Daytime Sleepiness

  • Livia G. Fregolente,
  • Lara Diem,
  • Jan D. Warncke,
  • Julia van der Meer,
  • Anina Schwarzwald,
  • Carolin Schäfer,
  • Helly Hammer,
  • Andrew Chan,
  • Robert Hoepner and
  • Claudio L. A. Bassetti

Sleep–wake disturbances are common in post-COVID-19 syndrome but lack extensive objective characterization. This study evaluated sleep–wake patterns in 31 patients with post-COVID-19 syndrome referred for fatigue and excessive daytime sle...

  • Review
  • Open Access
1,474 Views
11 Pages

Background: Chronic renal pain secondary to urological pathology can severely affect a patient’s quality of life. Utero Pelvic Junction Obstruction (UPJO) and Loin Pain Hematuria Syndrome (LPHS) are two conditions known to cause chronic renal p...

  • Perspective
  • Open Access
2,347 Views
7 Pages

Perceptual Uncertainty and Its Monitoring in Visual Snow Syndrome: A Multimodal Framework

  • Sophie De Beukelaer,
  • Antonia Klein and
  • Christoph J. Schankin

Neurobehavioral signatures, such as cortical hyperexcitability, thalamo-cortical dysrhythmia, and pulvinar dysfunction, appear to drive the persistent visual misperceptions in Visual Snow Syndrome (VSS). We propose that heightened perceptual uncertai...

  • Review
  • Open Access
1,107 Views
5 Pages

Migraine-Friendly Workspace: A Swiss Brain Health Initiative

  • Andreas R. Gantenbein,
  • Susanne Wegener,
  • Christoph J. Schankin and
  • Andreas K. Kleinschmidt

Migraine affects around one billion individuals worldwide, many in their working life, leading to significant personal and societal burdens. As modern working environments continue to change, so do the expectations of new generations of employees. Th...

  • Case Report
  • Open Access
6 Citations
1,443 Views
11 Pages

The Physiatrist in Intensive Care: Role, Tasks, and Critical Issues in a Clinical Case Report Analysis

  • Valerio Massimo Magro,
  • Andrea Sorbino,
  • Nicola Manocchio,
  • Concetta Ljoka and
  • Calogero Foti

Background: Disorders of Consciousness (DoC) following acute brain injuries, such as intracerebral hemorrhage, present significant clinical challenges in intensive care and rehabilitation settings. Early multidisciplinary interventions, including phy...

  • Brief Report
  • Open Access
1 Citations
901 Views
5 Pages

The Central Vein Sign as a Radiologic Tool to Predict the Diagnosis of Radiation Necrosis in Intracranial Metastatic Cancer Patients

  • Joseph P. Antonios,
  • Nana Adenu-Mensah,
  • Brianna C. Theriault,
  • Miguel Millares-Chavez,
  • Anita Huttner,
  • Mariam Aboian and
  • Veronica L. Chiang

Radiosurgery (SRS) is a primary treatment for intracranial metastatic disease, but it can lead to cerebral radiation necrosis (RN) in approximately 25% of cases. Unlike tumor progression (TP), which indicates a lack of response to treatment, RN sugge...

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Clin. Transl. Neurosci. - ISSN 2514-183X