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Citric Acid Production by Yarrowia lipolytica Yeast on Different Renewable Raw Materials

G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr-t Nauki, 5, 142290 Pushchino, Russia
Author to whom correspondence should be addressed.
Fermentation 2018, 4(2), 36;
Received: 28 April 2018 / Revised: 11 May 2018 / Accepted: 15 May 2018 / Published: 17 May 2018
(This article belongs to the Special Issue Yeast Biotechnology 2.0)
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The world market of citric acid (CA) is one of the largest and fastest growing markets in the biotechnological industry. Microbiological processes for CA production have usually used the mycelial fungi Aspergillus niger as a producer and molasses as a carbon source. In this paper, we propose methods for CA production from renewable carbon substrates (rapeseed oil, glucose, glycerol, ethanol, glycerol-containing waste of biodiesel industry and glucose-containing aspen waste) by the mutant strain Yarrowia lipolytica NG40/UV5. It was revealed that Y. lipolytica grew and synthesized CA using all tested raw materials. The obtained results are sufficient for industrial use of most of the raw materials studied for CA production. Using rapeseed oil, ethanol and raw glycerol (which is an important feedstock of biodiesel production), a high CA production (100–140 g L−1) was achieved. View Full-Text
Keywords: yeast Yarrowia lipolytica; citric acid (CA) production; raw materials yeast Yarrowia lipolytica; citric acid (CA) production; raw materials

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Morgunov, I.G.; Kamzolova, S.V.; Lunina, J.N. Citric Acid Production by Yarrowia lipolytica Yeast on Different Renewable Raw Materials. Fermentation 2018, 4, 36.

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