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Pediatric Invasive Candidiasis: Epidemiology and Diagnosis in Children

Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA
Academic Editor: John R. Perfect
J. Fungi 2016, 2(1), 5;
Received: 3 December 2015 / Revised: 4 January 2016 / Accepted: 5 January 2016 / Published: 8 January 2016
(This article belongs to the Special Issue Yeasts Are Beasts)
PDF [197 KB, uploaded 8 January 2016]


Pediatric patients present with differing underlying conditions and cytotoxic therapeutic protocols, so the differing epidemiology of invasive candidiasis in children versus adults is not surprising. Understanding the Candida species epidemiology is critical, as we often begin empiric therapy or therapy before antifungal susceptibilities are known. Reports with newer molecular diagnostic assays for invasive candidiasis are rare and require more study to develop firm pediatric-specific guidance. Antifungal treatment of pediatric candidiasis is reviewed in the context of larger epidemiologic studies and the few trials completed to date. View Full-Text
Keywords: pediatric; Candida; candidiasis; antifungal; diagnosis pediatric; Candida; candidiasis; antifungal; diagnosis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Steinbach, W.J. Pediatric Invasive Candidiasis: Epidemiology and Diagnosis in Children. J. Fungi 2016, 2, 5.

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