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Journal of Cardiovascular Development and Disease, Volume 9, Issue 10

2022 October - 51 articles

Cover Story: Transcatheter aortic valve implantation (TAVI) has become a valuable option for surgical aortic valve replacement in a wider spectrum of patients with aortic stenosis. Conduction abnormalities (CAs) requiring permanent pacemaker implantation (PPI) represent a frequent complication after TAVI, ranging between 3 and 26% in available studies. Several clinical and procedural factors have been identified as predictors of PPI after TAVI, including iatrogenic injury of the AV conduction system. Recent studies have shown that a significant number of patients are not strictly pacemaker-dependent over time. However, data on the features and time course of a possible AV conduction restoration during the post-operative period after TAVI are still lacking. The aim of this study was to investigate the prevalence and predictors of early CA recovery after AV node dysfunction requiring PPI post-TAVI. View this paper
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Articles (51)

  • Article
  • Open Access
35 Citations
5,539 Views
14 Pages

Colchicine in Cardiac Surgery: The COCS Randomized Clinical Trial

  • Vladimir Shvartz,
  • Tatyana Le,
  • Soslan Enginoev,
  • Maria Sokolskaya,
  • Artak Ispiryan,
  • Elena Shvartz,
  • Daria Nudel,
  • Naylyana Araslanova,
  • Andrey Petrosyan and
  • Elena Golukhova
  • + 3 authors

Background. In patients who underwent cardiac surgery, first-time postoperative atrial fibrillation (POAF) is associated with increased incidence of hospital-acquired complications and mortality. Systemic inflammation is one of confirmed triggers of...

(This article belongs to the Special Issue Cardiac Surgery: Outcomes, Management and Critical Care)
  • Systematic Review
  • Open Access
11 Citations
4,289 Views
14 Pages

Inadvertent Lead Malposition in the Left Heart during Implantation of Cardiac Electric Devices: A Systematic Review

  • Lorenzo Spighi,
  • Francesco Notaristefano,
  • Silvia Piraccini,
  • Giuseppe Giuffrè,
  • Alberto Barengo,
  • Matteo D’Ammando,
  • Salvatore Notaristefano,
  • Giuseppe Bagliani,
  • Gianluca Zingarini and
  • Claudio Cavallini
  • + 2 authors

Background. The inadvertent lead malposition in the left heart (ILMLH) is an under-recognized event, which may complicate the implantation of cardiac electronic devices (CIEDs). Methods. We investigated the clinical conditions associated with ILMLH a...

  • Review
  • Open Access
31 Citations
7,237 Views
24 Pages

Certainties and Uncertainties of Cardiac Magnetic Resonance Imaging in Athletes

  • Liliana Szabo,
  • Giulia Brunetti,
  • Alberto Cipriani,
  • Vencel Juhasz,
  • Francesca Graziano,
  • Kristof Hirschberg,
  • Zsofia Dohy,
  • Dorottya Balla,
  • Zsofia Drobni and
  • Hajnalka Vago
  • + 4 authors

Prolonged and intensive exercise induces remodeling of all four cardiac chambers, a physiological process which is coined as the “athlete’s heart”. This cardiac adaptation, however, shows overlapping features with non-ischemic cardi...

(This article belongs to the Special Issue Cardiovascular Disease in Athletes)
  • Correction
  • Open Access
1,611 Views
1 Page
  • Review
  • Open Access
12 Citations
4,973 Views
16 Pages

The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View

  • Maria L. Iovănescu,
  • Diana R. Florescu,
  • Andreea S. Marcu,
  • Ionuț Donoiu,
  • Sebastian Militaru,
  • Cristina Florescu,
  • Octavian Istrătoaie and
  • Constantin Militaru

Dilated cardiomyopathies (DCMs) are a heterogenous group of primary myocardial diseases, representing one of the leading causes of heart failure, and the main indication for heart transplantation. While the degree of left ventricular dilation and dys...

(This article belongs to the Topic Cardiac Imaging: State of the Art)
  • Article
  • Open Access
8 Citations
2,708 Views
11 Pages

Nutritional status is associated with prognosis in acute coronary syndrome (ACS) patients. Although the Global Registry of Acute Coronary Events (GRACE) risk score is regarded as a relevant risk predictor for the prognosis of ACS patients, nutritiona...

(This article belongs to the Section Cardiovascular Clinical Research)
  • Review
  • Open Access
20 Citations
5,977 Views
16 Pages

The Merits, Limitations, and Future Directions of Cost-Effectiveness Analysis in Cardiac MRI with a Focus on Coronary Artery Disease: A Literature Review

  • Taha A. Siddiqui,
  • Kiran S. Chamarti,
  • Leila C. Tou,
  • Gregory A. Demirjian,
  • Sarah Noorani,
  • Sydney Zink and
  • Muhammad Umair

Cardiac magnetic resonance (CMR) imaging has a wide range of clinical applications with a high degree of accuracy for many myocardial pathologies. Recent literature has shown great utility of CMR in diagnosing many diseases, often changing the course...

(This article belongs to the Special Issue Interventional Therapies and Management in Coronary Artery Disease)
  • Review
  • Open Access
4 Citations
2,974 Views
10 Pages

Role of Fibrinolysis in the Management of Patients with COVID-19 and Thromboembolic Complications: A Review

  • Patrycja Zając,
  • Karol Kaziród-Wolski,
  • Izabela Oleś,
  • Janusz Sielski and
  • Zbigniew Siudak

An impaired fibrinolytic process has been demonstrated in patients infected with SARS-CoV-2, including those in severe or critical condition. Disruption of fibrinolysis leads to fibrin deposition, which exacerbates inflammation and fibrosis and damag...

(This article belongs to the Special Issue Clinical Burden of Comorbidities on Cardiovascular System and Beyond)
  • Article
  • Open Access
5 Citations
3,576 Views
16 Pages

Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery

  • Shunsuke Saito,
  • Toshimi Sairenchi,
  • Shotaro Hirota,
  • Ken Niitsuma,
  • Shohei Yokoyama,
  • Yasuyuki Kanno,
  • Yuta Kanazawa,
  • Masahiro Tezuka,
  • Yusuke Takei and
  • Hirotsugu Fukuda
  • + 6 authors

Background This study compared the clinical outcomes of transcatheter (TAVR) and surgical (SAVR) aortic valve replacements, focusing on postoperative valvular performance assessed by echocardiography. Method and Results A total of 425 patients who un...

(This article belongs to the Special Issue Transcatheter Aortic Valve Implantation (TAVI))
  • Article
  • Open Access
1 Citations
2,183 Views
12 Pages

Previous studies indicated that prolonged lengths of hospitalization (LOH) during cardiac resynchronization therapy (CRT) implantation are associated with poorer physical status and higher in-hospital mortality. However, evidence on the impact of LOH...

(This article belongs to the Section Cardiovascular Clinical Research)
  • Article
  • Open Access
4 Citations
3,908 Views
16 Pages

(1) Background: The mechanism of viral myocarditis (VMC) progression to dilated cardiomyopathy (DCM) remains unclear. The aim of this study was to identify key genes in the progression of VMC to DCM, so as to find potential therapeutic drugs and prov...

  • Case Report
  • Open Access
2 Citations
2,794 Views
8 Pages

Minimally Invasive Surgical Repair of a Partial Atrioventricular Canal Defect in a 20-Year-Old Patient—A Case Report and Review of Literature

  • Horațiu Moldovan,
  • Cristian Bulescu,
  • Mihai Cacoveanu,
  • Cristian Voica,
  • Sabina Safta,
  • Mihai Goicea,
  • Irina Dobra,
  • Iulian Antoniac,
  • Daniela Gheorghiță and
  • Ondin Zaharia

The association of an ostium primum-type defect with a cleft anterior mitral valve is known in the medical literature as the partial form of an atrioventricular canal. We present a case report about a 20-year-old woman with minimal symptomatology tha...

  • Systematic Review
  • Open Access
14 Citations
6,445 Views
13 Pages

Left Atrial Appendage Thrombosis and Oral Anticoagulants: A Meta-Analysis of Risk and Treatment Response

  • Yun-Yung Cheng,
  • Shennie Tan,
  • Chien-Tai Hong,
  • Cheng-Chang Yang and
  • Lung Chan

Background: Left atrial appendage thrombus (LAAT) is the main cause of cardioembolism in patients with nonvalvular atrial fibrillation (AF). Emerging evidence indicates that direct oral anticoagulants (DOACs) may be a preferred, safer choice for pati...

(This article belongs to the Special Issue New Insights into Antithrombotic Therapy for Cardio- and Cerebrovascular Disease: From Molecular Mechanisms to Clinical Application)
  • Review
  • Open Access
11 Citations
6,718 Views
17 Pages

Multimodality Imaging in the Detection of Ischemic Heart Disease in Women

  • Sean Paul Gaine,
  • Garima Sharma,
  • Albree Tower-Rader,
  • Mina Botros,
  • Lara Kovell,
  • Anushri Parakh,
  • Malissa J. Wood and
  • Colleen M. Harrington

Women with coronary artery disease tend to have a worse short and long-term prognosis relative to men and the incidence of atherosclerotic cardiovascular disease is increasing. Women are less likely to present with classic anginal symptoms when compa...

(This article belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)
  • Article
  • Open Access
8 Citations
3,293 Views
11 Pages

Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair

  • Marine Gaudry,
  • Carine Guivier-Curien,
  • Arnaud Blanchard,
  • Alizée Porto,
  • Laurence Bal,
  • Virgile Omnes,
  • Mariangela De Masi,
  • Charlotte Lu,
  • Alexis Jacquier and
  • Valerie Deplano
  • + 1 author

Background: The aim of this study was to evaluate the aortic diameter and volume during the first year after a type A repair to predict the long-term prognosis of a residual aortic dissection (RAD). Methods: All patients treated in our center for an...

  • Case Report
  • Open Access
1 Citations
2,281 Views
7 Pages

There have been several reports on the identification of the stage of transthyretin amyloid cardiomyopathy (ATTR-CM); however, a staging system for ATTR-CM has not yet been established. An 83-year-old woman was referred to our department about ten ye...

(This article belongs to the Section Acquired Cardiovascular Disease)
  • Review
  • Open Access
36 Citations
7,549 Views
20 Pages

May Strenuous Endurance Sports Activity Damage the Cardiovascular System of Healthy Athletes? A Narrative Review

  • Francesca Graziano,
  • Vencel Juhasz,
  • Giulia Brunetti,
  • Alberto Cipriani,
  • Liliana Szabo,
  • Béla Merkely,
  • Domenico Corrado,
  • Flavio D’Ascenzi,
  • Hajnalka Vago and
  • Alessandro Zorzi

The positive effects of physical activity are countless, not only on the cardiovascular system but on health in general. However, some studies suggest a U-shape relationship between exercise volume and effects on the cardiovascular system. On the bas...

(This article belongs to the Special Issue Cardiovascular Disease in Athletes)
  • Article
  • Open Access
10 Citations
4,061 Views
9 Pages

Association between Serum Uric Acid and Hypertension in a Large Cross-Section Study in a Chinese Population

  • Yang He,
  • Du Chen,
  • Jing-Ping Xu,
  • Jun Jin,
  • Jun Wang,
  • Cong Geng and
  • Yong-Ming He

Background: The association of serum uric acid (SUA) with hypertension has been well established in Caucasian populations. However, its association with hypertension in Chinese remained to be clarified. Methods: Consecutive patients, homogeneous in C...

  • Article
  • Open Access
8 Citations
3,769 Views
14 Pages

Background: The relationship between diastolic blood pressure (DBP), risk factors, and stroke severity in acute ischemic stroke (AIS) patients treated in a telestroke network is not fully understood. The present study aims to determine the effect of...

(This article belongs to the Special Issue Models and Methods for Computational Cardiology)
  • Article
  • Open Access
5 Citations
4,520 Views
13 Pages

Clinical Determinants and Barriers to Cardiac Rehabilitation Enrollment of Patients with Heart Failure with Reduced Ejection Fraction: A Single-Center Study in Portugal

  • André Alexandre,
  • Cristine Schmidt,
  • Andreia Campinas,
  • Catarina Gomes,
  • Sandra Magalhães,
  • José Preza-Fernandes,
  • Severo Torres and
  • Mário Santos

Despite cardiac rehabilitation (CR) being a recommended treatment for patients with heart failure with reduced ejection fraction (HFrEF), it is still underused. This study investigated the clinical determinants and barriers to enrollment in a CR prog...

(This article belongs to the Special Issue Cardiac Rehabilitation: State of the Art and Perspectives)
  • Systematic Review
  • Open Access
3 Citations
3,815 Views
11 Pages

Background: New randomized trials and modalities in guiding percutaneous coronary intervention (PCI) have become available. Objective: We aimed to compare the clinical outcomes of coronary angiography (CAG), intravascular ultrasound (IVUS), optical c...

(This article belongs to the Section Cardiac Surgery)
  • Article
  • Open Access
8 Citations
5,340 Views
13 Pages

Comparison of Estimated LDL Cholesterol Equations with Direct Measurement in Patients with Angiographically Confirmed Coronary Artery Disease

  • Boqun Shi,
  • Hao-Yu Wang,
  • Dong Yin,
  • Chenggang Zhu,
  • Lei Feng,
  • Hongjian Wang,
  • Lei Jia,
  • Rui Fu,
  • Chenxi Song and
  • Ke-Fei Dou
  • + 3 authors

Background and aims: Our goals in the study were to (1) quantify the discordance in LDL-C levels between equations (the Friedewald, Sampson, and Martin/Hopkins equations) and compare them with direct LDL-C (dLDL-C); and (2) explore the proportion of...

  • Article
  • Open Access
3 Citations
3,304 Views
13 Pages

The purpose of this study was to investigate the influence of C1QL1 on atherosclerosis as well as the transcriptomic alteration of the aorta. While complement C1ql-like 1 (C1QL1) is one of the C1q/tumor-necrosis-factor-related protein (CTRP) family m...

(This article belongs to the Section Genetics)
  • Review
  • Open Access
8 Citations
6,195 Views
19 Pages

P2Y12 Inhibitor Monotherapy after Percutaneous Coronary Intervention

  • Xuan Zhou,
  • Dominick J. Angiolillo and
  • Luis Ortega-Paz

In patients with acute and chronic coronary artery disease undergoing percutaneous coronary intervention (PCI), dual antiplatelet therapy (DAPT) has been the cornerstone of pharmacotherapy for the past two decades. Although its antithrombotic benefit...

(This article belongs to the Special Issue New Insights into Antithrombotic Therapy for Cardio- and Cerebrovascular Disease: From Molecular Mechanisms to Clinical Application)
  • Article
  • Open Access
2 Citations
4,283 Views
10 Pages

Long-Term Outcomes Stratified by Age in Patients with a Mechanical versus Biological Mitral Valve Replacement

  • Gábor Veres,
  • Kálmán Benke,
  • Roland Stengl,
  • Petra Weber,
  • Ereva Marina,
  • Gábor Szabó and
  • Matthias Karck

Objectives: Balancing anticoagulation and reoperation risks determines prostheses choice (mechanical/biological) for mitral valve replacement. We aimed to re-evaluate the outcomes after biological versus mechanical mitral valve replacement. Methods:...

  • Article
  • Open Access
13 Citations
3,127 Views
11 Pages

Feasibility of Left Bundle Branch Area Pacing Combined with Atrioventricular Node Ablation in Atrial Fibrillation Patients with Heart Failure

  • Qi-Qi Jin,
  • Cheng Zheng,
  • Yao-Ji Wang,
  • Jia-Xuan Lin,
  • Dao-Zhu Wu,
  • Jia-Feng Lin and
  • Xue-Qiang Guan

Background: Pacemaker implantation combined with atrioventricular node ablation (AVNA) could be a practical choice for atrial fibrillation (AF) patients with heart failure (HF). Left bundle branch area pacing (LBBaP) has been widely reported. Objecti...

(This article belongs to the Topic Atrial Fibrillation: State-of-the-Art Techniques and Future Perspectives for Diagnosis, Rhythm Control, and Stroke Prophylaxis)
  • Article
  • Open Access
5 Citations
3,106 Views
17 Pages

Frequency, Risk Factors, and Clinical Outcomes of Late-Onset Atrial Flutter in Patients after Heart Transplantation

  • Ann-Kathrin Rahm,
  • Susanne Reinhardt,
  • Matthias Helmschrott,
  • Fabrice F. Darche,
  • Tom Bruckner,
  • Patrick Lugenbiel,
  • Dierk Thomas,
  • Philipp Ehlermann,
  • Wiebke Sommer and
  • Rasmus Rivinius
  • + 2 authors

Aims: Atrial flutter (AFL) is a common late-onset complication after heart transplantation (HTX) and is associated with worse clinical outcomes. Methods: This study investigated the frequency, risk factors, and outcomes of late-onset post-transplant...

(This article belongs to the Collection Current Challenges in Heart Failure and Cardiac Transplantation)
  • Article
  • Open Access
15 Citations
4,128 Views
12 Pages

Limitations of Baseline Impedance, Impedance Drop and Current for Radiofrequency Catheter Ablation Monitoring: Insights from In silico Modeling

  • Ramiro M. Irastorza,
  • Timothy Maher,
  • Michael Barkagan,
  • Rokas Liubasuskas,
  • Juan J. Pérez,
  • Enrique Berjano and
  • Andre d’Avila

Background: Baseline impedance, radiofrequency current, and impedance drop during radiofrequency catheter ablation are thought to predict effective lesion formation. However, quantifying the contributions of local versus remote impedances provides in...

(This article belongs to the Special Issue Catheter Ablation of Cardiac Arrhythmias: Practices and Outcomes)
  • Review
  • Open Access
10 Citations
4,352 Views
18 Pages

New Biomarkers and Their Potential Role in Heart Failure Treatment Optimisation—An African Perspective

  • Marheb Badianyama,
  • Dineo Mpanya,
  • Umar Adamu,
  • Farai Sigauke,
  • Samantha Nel and
  • Nqoba Tsabedze

Heart failure is a clinical syndrome resulting from various cardiovascular diseases of different aetiologies and pathophysiology. These varying pathologies involve several complex mechanisms that lead to the activation of the neurohumoral system, inf...

(This article belongs to the Special Issue Therapeutic Strategies for Heart Failure)
  • Article
  • Open Access
10 Citations
3,607 Views
11 Pages

Plasma Levels of Intact Parathyroid Hormone and Congestion Burden in Heart Failure: Clinical Correlations and Prognostic Role

  • Pietro Scicchitano,
  • Massimo Iacoviello,
  • Andrea Passantino,
  • Michele Gesualdo,
  • Francesco Trotta,
  • Marco Basile,
  • Micaela De Palo,
  • Piero Guida,
  • Claudio Paolillo and
  • Francesco Massari
  • + 3 authors

Circulating parathyroid hormone (PTH) concentrations increase in heart failure (HF) and are related to disease severity. The relationship between PTH and congestion is still a matter of debate. The objective of this analysis was to evaluate the role...

(This article belongs to the Section Electrophysiology and Cardiovascular Physiology)
  • Article
  • Open Access
13 Citations
3,728 Views
13 Pages

Prognostic Relevance of Cardiopulmonary Exercise Testing for Patients with Chronic Thromboembolic Pulmonary Hypertension

  • Ralf Ewert,
  • Till Ittermann,
  • Delia Schmitt,
  • Elena Pfeuffer-Jovic,
  • Johannes Stucke,
  • Kristin Tausche,
  • Michael Halank,
  • Jörg Winkler,
  • Andreas Hoheisel and
  • Matthias Held
  • + 6 authors

Background: Following acute pulmonary embolism (PE), a relevant number of patients experience decreased exercise capacity which can be associated with disturbed pulmonary perfusion. Cardiopulmonary exercise testing (CPET) shows several patterns typic...

(This article belongs to the Special Issue Cardiac Surgery: Outcomes, Management and Critical Care)
  • Article
  • Open Access
9 Citations
4,794 Views
14 Pages

Cardiovascular Involvement in Pediatric FLNC Variants: A Case Series of Fourteen Patients

  • Anwar Baban,
  • Viola Alesi,
  • Monia Magliozzi,
  • Giovanni Parlapiano,
  • Silvia Genovese,
  • Marianna Cicenia,
  • Sara Loddo,
  • Valentina Lodato,
  • Luca Di Chiara and
  • Fabrizio Drago
  • + 5 authors

Filamin C is a protein specifically expressed in myocytes and cardiomyocytes and is involved in several biological functions, including sarcomere contractile activity, signaling, cellular adhesion, and repair. FLNC variants are associated with differ...

(This article belongs to the Special Issue Pediatric Cardiomyopathies: From Genotype to Phenotype)
  • Article
  • Open Access
11 Citations
4,176 Views
11 Pages

Comparison of Suture-Based and Collagen-Based Vascular Closure Devices for Large Bore Arteriotomies—A Meta-Analysis of Bleeding and Vascular Outcomes

  • Sumit Sohal,
  • Sheetal Vasundara Mathai,
  • Sanjana Nagraj,
  • Krishna Kurpad,
  • Kandarp Suthar,
  • Harsh Mehta,
  • Komaldeep Kaur,
  • Najam Wasty,
  • Sergio Waxman and
  • Rajiv Tayal
  • + 2 authors

Background: Large bore access procedures rely on vascular closure devices to minimize access site complications. Suture-based vascular closure devices (S-VCD) such as ProGlide and ProStar XL have been readily used, but recently, newer generation coll...

(This article belongs to the Special Issue Transcatheter Aortic Valve Implantation (TAVI))
  • Article
  • Open Access
5 Citations
3,262 Views
13 Pages

The CCR2+ Monocyte Subsets Increase in Obese Boys but Not Girls with Abnormally High Carotid Intima-Media Thickness: A Pilot Study

  • María José Garcés-Hernández,
  • Karen Pedraza-Escudero,
  • Nayely Garibay-Nieto,
  • Joselin Hernández-Ruiz,
  • Jessica Lakshmi Prieto-Chávez,
  • Lourdes Andrea Arriaga-Pizano,
  • Eréndira Villanueva-Ortega,
  • Galileo Escobedo,
  • Aaron Noe Manjarrez-Reyna and
  • Gloria Queipo-García
  • + 2 authors

The differential contribution of monocyte subsets expressing the C-C chemokine receptor 2 (CCR2) to subclinical atherosclerosis in girls and boys is unclear. In this pilot study, we compared classical, intermediate, and nonclassical monocyte subsets...

(This article belongs to the Section Cardiac Development and Regeneration)
  • Article
  • Open Access
17 Citations
7,032 Views
13 Pages

The Association of Triglyceride to High-Density Lipoprotein Cholesterol Ratio with High-Risk Coronary Plaque Characteristics Determined by CT Angiography and Its Risk of Coronary Heart Disease

  • Yuji Koide,
  • Toru Miyoshi,
  • Takahiro Nishihara,
  • Mitsutaka Nakashima,
  • Keishi Ichikawa,
  • Takashi Miki,
  • Kazuhiro Osawa and
  • Hiroshi Ito

The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio is an independent risk index for cardiovascular events. This study aimed to evaluate the association between TG/HDL-C ratio and coronary plaque characteristics as seen on coron...

(This article belongs to the Special Issue Atherosclerosis: Current Concepts of Genetic, Epigenetic and Environmental Risk Factors)
  • Systematic Review
  • Open Access
21 Citations
5,999 Views
17 Pages

The Comparison of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training after Coronary Artery Bypass Graft: A Systematic Review of Recent Studies

  • Billie Schulté,
  • Lisa Nieborak,
  • Franck Leclercq,
  • Jorge Hugo Villafañe,
  • Eleuterio A. Sánchez Romero and
  • Camilo Corbellini

Currently, no international consensus on cardiac rehabilitation exists, leading to great variability in the intensity recommendations for training programs for cardiac patients, including those undergoing coronary artery bypass graft surgery (CABG)....

(This article belongs to the Special Issue Cardiac Rehabilitation: State of the Art and Perspectives)
  • Article
  • Open Access
7 Citations
3,341 Views
12 Pages

Evaluation of Isolation Area, Myocardial Injury and Left Atrial Function Following High-Power Short-Duration Radiofrequency or Second-Generation Cryoballoon Ablation for Atrial Fibrillation

  • Krisztian Istvan Kassa,
  • Zsofia Nagy,
  • Daniel Simkovits,
  • Zsuzsanna Kis,
  • Tamas Ferenci,
  • Zoltan Som,
  • Csaba Foldesi and
  • Attila Kardos

This randomized study aims to compare the left atrial (LA) lesion size, function, and tissue damage following pulmonary vein isolation (PVI) by high-power short-duration (HPSD) radiofrequency (RF) and second-generation cryoballoon (CB2) ablation. We...

(This article belongs to the Special Issue Catheter Ablation of Cardiac Arrhythmias: Practices and Outcomes)
  • Article
  • Open Access
65 Citations
8,362 Views
30 Pages

Attention-Based UNet Deep Learning Model for Plaque Segmentation in Carotid Ultrasound for Stroke Risk Stratification: An Artificial Intelligence Paradigm

  • Pankaj K. Jain,
  • Abhishek Dubey,
  • Luca Saba,
  • Narender N. Khanna,
  • John R. Laird,
  • Andrew Nicolaides,
  • Mostafa M. Fouda,
  • Jasjit S. Suri and
  • Neeraj Sharma

Stroke and cardiovascular diseases (CVD) significantly affect the world population. The early detection of such events may prevent the burden of death and costly surgery. Conventional methods are neither automated nor clinically accurate. Artificial...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence in Cardiovascular Medicine)
  • Article
  • Open Access
5 Citations
2,573 Views
12 Pages

This study aims at examining the chronological development of hospitalized cardiovascular and COVID-19 patients and comparing the effects on related sub-disciplines and main diagnoses for pre-pandemic (2017–2019) and pandemic (2020–2021)...

(This article belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)
  • Article
  • Open Access
2 Citations
4,693 Views
10 Pages

Short-Term Atrioventricular Dysfunction Recovery after Post-TAVI Pacemaker Implantation

  • Gaetano Pinnacchio,
  • Eleonora Ruscio,
  • Erica Rocco,
  • Carlo Trani,
  • Francesco Burzotta,
  • Cristina Aurigemma,
  • Enrico Romagnoli,
  • Roberto Scacciavillani,
  • Maria Lucia Narducci and
  • Gemma Pelargonio
  • + 5 authors

Permanent pacemaker implantation (PPI) represents a frequent complication after transcatheter aortic valve implantation (TAVI) due to atrio-ventricular (AV) node injury. Predictors of early AV function recovery were investigated. We analyzed 50 conse...

(This article belongs to the Special Issue Transcatheter Aortic Valve Implantation (TAVI))
  • Article
  • Open Access
5 Citations
3,274 Views
10 Pages

Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease

  • Kakeru Hashimoto,
  • Akihiro Hirashiki,
  • Koharu Oya,
  • Junpei Sugioka,
  • Shunya Tanioku,
  • Kenji Sato,
  • Ikue Ueda,
  • Naoki Itoh,
  • Manabu Kokubo and
  • Izumi Kondo
  • + 2 authors

Life-space activities are a measure of daily activity level. Here, we examined the association between life-space activities and prognosis in 129 cardiovascular diseases (CVD) patients 65 years of age or older (average age, 79.2 ± 7.6 years; m...

(This article belongs to the Special Issue Cardiac Rehabilitation: State of the Art and Perspectives)
  • Article
  • Open Access
8 Citations
3,208 Views
10 Pages

Background: Patients with acute coronary syndrome (ACS) still have a high risk of recurrence of major adverse cardiovascular and cerebrovascular events (MACCE). However, there are rare studies on the prediction of MACCE in patients with ACS using lip...

(This article belongs to the Topic Biomarkers in Cardiovascular Disease—Chances and Risks)
  • Article
  • Open Access
8 Citations
3,044 Views
13 Pages

Atrial septal defect (ASD) is one of the most common forms of congenital heart disease (CHD). Genetic variants in the coding region of the CITED2 gene are known to be significantly correlated with CHD, but the role of variants in the promoter region...

  • Article
  • Open Access
9 Citations
6,193 Views
9 Pages

Exercise and Escitalopram in the Treatment of Anxiety in Patients with Coronary Heart Disease: One Year Follow-Up of the UNWIND Randomized Clinical Trial

  • James A. Blumenthal,
  • Patrick J. Smith,
  • Wei Jiang,
  • Alan Hinderliter,
  • Lana L. Watkins,
  • Benson M. Hoffman,
  • William E. Kraus,
  • Stephanie Mabe,
  • Lawrence Liao and
  • Andrew Sherwood
  • + 1 author

Anxiety is common among patients with coronary heart disease (CHD) and is associated with a worse prognosis. UNWIND was a 12-week randomized clinical trial comparing exercise and escitalopram to placebo on measures of anxiety, depression, and CHD bio...

(This article belongs to the Special Issue Recent Advances in Sports Cardiology)
  • Article
  • Open Access
15 Citations
3,182 Views
22 Pages

Pulsed field ablation (PFA) is a promising new ablation modality for the treatment of atrial fibrillation (AF); however, the effect of fiber orientation on the ablation characteristics of PFA in AF treatment is still unclear, which is likely an essen...

(This article belongs to the Special Issue Catheter Ablation of Cardiac Arrhythmias: Practices and Outcomes)
  • Review
  • Open Access
1 Citations
2,776 Views
7 Pages

The Medical versus Zoological Concept of Outflow Tract Valves of the Vertebrate Heart

  • Valentín Sans-Coma,
  • Bárbara Pozo-Vilumbrales,
  • María Carmen Fernández,
  • Miguel Á. López-Unzu,
  • María Teresa Soto-Navarrete,
  • Ana Carmen Durán,
  • Josep M. Arqué and
  • Borja Fernández

The anatomical elements that in humans prevent blood backflow from the aorta and pulmonary artery to the left and right ventriclesare the aortic and pulmonary valves, respectively. Each valve regularly consists of three leaflets (cusps), each support...

(This article belongs to the Section Basic and Translational Cardiovascular Research)
  • Review
  • Open Access
15 Citations
7,019 Views
10 Pages

Alcohol and Cardiovascular Diseases—Do the Consumption Pattern and Dose Make the Difference?

  • Małgorzata Chudzińska,
  • Łukasz Wołowiec,
  • Joanna Banach,
  • Daniel Rogowicz and
  • Grzegorz Grześk

Excessive consumption of alcohol is not only a social problem, but it also significantly increases the morbidity and mortality rates of many societies. A correlation has been demonstrated between alcohol consumption and increased mortality from cance...

(This article belongs to the Special Issue Diet and Cardiovascular Diseases—Current Views and Trends)
  • Article
  • Open Access
1 Citations
2,843 Views
14 Pages

Background: We aimed to demonstrate whether the preoperative transthoracic echocardiography index (TTEI) could improve the predictive value of clinical parameters for cardiac valve surgery-associated acute kidney injury (CVS−AKI). Methods: A to...

(This article belongs to the Special Issue Cardiac Surgery: Outcomes, Management and Critical Care)
  • Perspective
  • Open Access
4 Citations
5,187 Views
11 Pages

Hypoplastic left heart syndrome (HLHS) is among the most severe cardiovascular malformations and understanding its causes is crucial to making progress in prevention and treatment. Genetic analysis is a broadly useful tool for dissecting complex caus...

(This article belongs to the Special Issue Hypoplastic Left Heart Syndrome: Etiology, Pathogenesis, Management and The Future)
  • Article
  • Open Access
2 Citations
3,358 Views
7 Pages

The Acute-Phase Ambulation Program Improves Clinical Outcome for Acute Heart Failure

  • Yusuke Funato,
  • Yuji Kono,
  • Hideki Kawai,
  • Meiko Hoshino,
  • Akira Yamada,
  • Takashi Muramatsu,
  • Masahide Harada,
  • Hiroshi Takahashi,
  • Yohei Otaka and
  • Hideo Izawa
  • + 1 author

It remains unclear whether the acute-phase ambulation program (AAP) improves the prognosis of heart failure (HF) patients. We examined the association between the initiation of AAP and the prognosis of patients with worsening HF. We enrolled 560 cons...

(This article belongs to the Special Issue Cardiac Rehabilitation: State of the Art and Perspectives)

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425