Journal of Cardiovascular Development and Disease, Volume 9, Issue 11
2022 November - 45 articles
Cover Story: While individual 3D imaging methods can provide special types of micro-morphological and functional information about developing organs, a synthesis of different data types is necessary to understand normal and pathological development. We present a detailed workflow for specimen-specific correlation of dynamic in vivo optical coherence tomography (OCT) imaging of the developing chick heart with high-detail 3D X-ray microtomography (micro-CT) data. Our workflow allows for overview and dynamic imaging of the whole heart over the cardiac cycle and can provide 3D virtual histology information in intact specimens. This multimodal approach has the potential to provide new and valuable insights into cardiac morphogenesis by providing unique and complementary information only achievable through the correlation of these data. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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