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Journal of Cardiovascular Development and Disease, Volume 8, Issue 6

June 2021 - 13 articles

Cover Story: Left–right patterning of the heart is essential for its correct anatomy, function and connection with neighbouring organs. Asymmetric patterning begins soon after formation of the symmetrical heart fields, when left–right axis signalling reaches the tissue. Heart development is, therefore, controlled by overall left–right axis patterning, and, after this information is relayed, the heart is imbued with tissue-intrinsic asymmetry that instructs later development. This patterning is highly conserved across vertebrate species and the zebrafish model has provided a wealth of information both confirming and extending our understanding of the genetic and cellular regulation of asymmetric heart development. View this paper.
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Articles (13)

  • Case Report
  • Open Access
2,504 Views
5 Pages

“Never Trust to General Impressions, My Boy, but Concentrate Yourself upon Details”: An Unusual and Challenging Presentation of Pheochromocytoma

  • Umberto Barbero,
  • Mario Matta,
  • Mirko Parasiliti Caprino,
  • Francesca Maletta,
  • Giuseppe Giraudo,
  • Simone Frea,
  • Michele De Benedictis and
  • Mauro Maccario

We present the case of a 45-year-old woman admitted to our unit with acute heart failure and cardiogenic shock, requiring an intra-aortic balloon pump insertion and inotropes and vasopressors infusion. Despite such treatment, the patient developed mu...

  • Review
  • Open Access
17 Citations
7,460 Views
14 Pages

How Cardiac Embryology Translates into Clinical Arrhythmias

  • Mathilde R. Rivaud,
  • Michiel Blok,
  • Monique R. M. Jongbloed and
  • Bastiaan J. Boukens

The electrophysiological signatures of the myocardium in cardiac structures, such as the atrioventricular node, pulmonary veins or the right ventricular outflow tract, are established during development by the spatial and temporal expression of trans...

  • Article
  • Open Access
7 Citations
3,638 Views
9 Pages

Comparison of Left Atrial Appendage Occlusion versus Non-Vitamin-K Antagonist Oral Anticoagulation in High-Risk Atrial Fibrillation: An Update

  • Shaojie Chen,
  • K. R. Julian Chun,
  • Zhiyu Ling,
  • Shaowen Liu,
  • Lin Zhu,
  • Jiazhi Wang,
  • Alexandra Schratter,
  • Willem-Jan Acou,
  • Márcio Galindo Kiuchi and
  • Yuehui Yin
  • + 1 author

Transcatheter left atrial appendage occlusion (LAAO) is non-inferior to vitamin K antagonists (VKAs) in preventing thromboembolic events in atrial fibrillation (AF). Non-vitamin K antagonists (NOACs) have an improved safety profile over VKAs; however...

  • Commentary
  • Open Access
6 Citations
3,441 Views
6 Pages

Society and medical practice have been restructured dramatically to avoid further spread of the COVID-19 virus; telehealth/telemedicine, mask wearing, and nationwide social distancing practices have become widespread. However, we still face unprecede...

  • Case Report
  • Open Access
1 Citations
3,281 Views
6 Pages

Both cannabis and amphetamine are the most commonly used illegal substances worldwide and are associated with a number of adverse cardiovascular effects including transient coronary vasospasm. Here, we present the case of a 39-year-old male admitted...

  • Case Report
  • Open Access
8 Citations
3,094 Views
6 Pages

Acute Myocardial Infarction Due to Microvascular Obstruction in a Young Woman Who Recently Recovered from COVID-19 Infection

  • Abukar Mohamed Ali,
  • Daanyaal Wasim,
  • Terje H. Larsen,
  • Nigussie Bogale,
  • Øyvind Bleie and
  • Sahrai Saeed

Although cardiovascular complications are common in hospitalized COVID-19 patients, those with milder cases who recovered at home are less studied. Here, we report the case of a young woman who recently recovered from COVID-19 at home. A week after r...

  • Review
  • Open Access
11 Citations
5,594 Views
12 Pages

The heart is laterally asymmetric. Not only is it positioned on the left side of the body but the organ itself is asymmetric. This patterning occurs across scales: at the organism level, through left–right axis patterning; at the organ level, where t...

  • Article
  • Open Access
11 Citations
3,356 Views
20 Pages

Machine Learning for Predicting Mortality in Transcatheter Aortic Valve Implantation: An Inter-Center Cross Validation Study

  • Marco Mamprin,
  • Ricardo R. Lopes,
  • Jo M. Zelis,
  • Pim A. L. Tonino,
  • Martijn S. van Mourik,
  • Marije M. Vis,
  • Svitlana Zinger,
  • Bas A. J. M. de Mol and
  • Peter H. N. de With

Current prognostic risk scores for transcatheter aortic valve implantation (TAVI) do not benefit yet from modern machine learning techniques, which can improve risk stratification of one-year mortality of patients before TAVI. Despite the advancement...

  • Article
  • Open Access
15 Citations
3,772 Views
14 Pages

The Association of Lipoprotein(a) and Circulating Monocyte Subsets with Severe Coronary Atherosclerosis

  • Olga I. Afanasieva,
  • Anastasya Yu. Filatova,
  • Tatiana I. Arefieva,
  • Elena A. Klesareva,
  • Alexandra V. Tyurina,
  • Natalia V. Radyukhina,
  • Marat V. Ezhov and
  • Sergei N. Pokrovsky

Background and aims: Chronic inflammation associated with the uncontrolled activation of innate and acquired immunity plays a fundamental role in all stages of atherogenesis. Monocytes are a heterogeneous population and each subset contributes differ...

  • Article
  • Open Access
13 Citations
3,834 Views
25 Pages

An association between movement behavior (MB) components (sleep time (ST), physical activity (PA) and sedentary behavior (SB)) and the state of the cardiovascular (CV) system in children has been postulated. However, it is still controversial whether...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425Creative Common CC BY license